"Myosin Subfragments" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Parts of the myosin molecule resulting from cleavage by proteolytic enzymes (PAPAIN; TRYPSIN; or CHYMOTRYPSIN) at well-localized regions. Study of these isolated fragments helps to delineate the functional roles of different parts of myosin. Two of the most common subfragments are myosin S-1 and myosin S-2. S-1 contains the heads of the heavy chains plus the light chains and S-2 contains part of the double-stranded, alpha-helical, heavy chain tail (myosin rod).
| Descriptor ID |
D015879
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| MeSH Number(s) |
D05.750.078.730.475.300 D12.776.210.500.600.300 D12.776.220.525.475.300
|
| Concept/Terms |
Heavy Meromyosin Subfragment-2- Heavy Meromyosin Subfragment-2
- Heavy Meromyosin Subfragment 2
- Meromyosin Subfragment-2, Heavy
- Subfragment-2, Heavy Meromyosin
- Myosin Subfragment-2
- Myosin Subfragment 2
- Subfragment-2, Myosin
- Myosin S-2
- Myosin S 2
Heavy Meromyosin Subfragment-1- Heavy Meromyosin Subfragment-1
- Heavy Meromyosin Subfragment 1
- Meromyosin Subfragment-1, Heavy
- Subfragment-1, Heavy Meromyosin
- Myosin Subfragment-1
- Myosin Subfragment 1
- Subfragment-1, Myosin
- ATPase, Actin-S1
- Actin-S1 ATPase
- Myosin S-1
- Myosin S 1
- Actin S1 ATPase
- ATPase, Actin S1
- Actomyosin Subfragment 1 ATPase
|
Below are MeSH descriptors whose meaning is more general than "Myosin Subfragments".
Below are MeSH descriptors whose meaning is more specific than "Myosin Subfragments".
This graph shows the total number of publications written about "Myosin Subfragments" by people in this website by year, and whether "Myosin Subfragments" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myosin Subfragments" by people in Profiles.
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Myosin light chain kinase steady-state kinetics: comparison of smooth muscle myosin II and nonmuscle myosin IIB as substrates. Cell Biochem Funct. 2016 Oct; 34(7):469-474.
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Rapid discovery of inhibitors of Toxoplasma gondii using hybrid structure-based computational approach. J Comput Aided Mol Des. 2011 May; 25(5):403-11.
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Beta-myosin heavy chain gene mutations in familial hypertrophic cardiomyopathy: the usual suspect? Circ Res. 2002 Feb 22; 90(3):246-7.
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Assays for actin sliding movement over myosin-coated surfaces. Methods Enzymol. 1991; 196:399-416.
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Expression of myosin and actin in Escherichia coli. Methods Enzymol. 1991; 196:368-89.
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The myosin step size: measurement of the unit displacement per ATP hydrolyzed in an in vitro assay. Proc Natl Acad Sci U S A. 1990 Sep; 87(18):7130-4.
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Subtilisin cleavage of actin inhibits in vitro sliding movement of actin filaments over myosin. J Cell Biol. 1990 Aug; 111(2):465-70.
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Complete cDNA sequence of rat atrial myosin light chain 1: patterns of expression during development and with hypertension. Nucleic Acids Res. 1990 Mar 25; 18(6):1581-6.
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Coexpression and assembly of myosin heavy chain and myosin light chain in Escherichia coli. Proc Natl Acad Sci U S A. 1988 Oct; 85(19):7270-3.
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Myosin subfragment-1 is sufficient to move actin filaments in vitro. Nature. 1987 Aug 6-12; 328(6130):536-9.