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Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.
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Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.
Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis. Cell. 2011 Oct 14; 147(2):306-19.
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PubMed
subject areas
Amino Acid Sequence
Animals
Base Sequence
Benzamides
Cells, Cultured
Fusion Proteins, bcr-abl
Humans
Imatinib Mesylate
Isoleucine
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Mice
Models, Molecular
Molecular Sequence Data
Piperazines
Protein Kinase Inhibitors
Protein-Tyrosine Kinases
Pyrimidines
Signal Transduction
src Homology Domains