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Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.
SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion.
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SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion.
SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion. Am J Physiol Endocrinol Metab. 2012 Mar 15; 302(6):E714-23.
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PubMed
subject areas
Animals
Biotinylation
Cells, Cultured
Cyclic GMP
DNA, Complementary
Down-Regulation
Enzyme-Linked Immunosorbent Assay
Fluorescence Resonance Energy Transfer
Fluorescent Antibody Technique
Glucagon-Like Peptide 1
Glucose
Humans
Immunoprecipitation
Incretins
Insulin
Insulin-Secreting Cells
Membrane Proteins
Mice
Mice, Inbred C57BL
Real-Time Polymerase Chain Reaction
Small Ubiquitin-Related Modifier Proteins
Stimulation, Chemical
Transfection
Ubiquitin-Conjugating Enzymes
authors with profiles
Louis Philipson
Sindhu Rajan