"Leukotriene D4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990)
| Descriptor ID |
D017998
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| MeSH Number(s) |
D10.251.355.255.100.450.855.461 D10.251.355.310.166.887.855.461 D23.469.050.175.450.725.415
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Leukotriene D4".
Below are MeSH descriptors whose meaning is more specific than "Leukotriene D4".
This graph shows the total number of publications written about "Leukotriene D4" by people in this website by year, and whether "Leukotriene D4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukotriene D4" by people in Profiles.
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Leukotriene D4 activates {beta}2-integrin adhesion in human polymorphonuclear leukocytes. Eur Respir J. 2010 Feb; 35(2):402-9.
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Leukotriene pathways and in vitro adenotonsillar cell proliferation in children with obstructive sleep apnea. Chest. 2009 May; 135(5):1142-1149.
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Eosinophil chemotaxis inhibited by 5-lipoxygenase blockade and leukotriene receptor antagonism. Am J Respir Crit Care Med. 1997 Apr; 155(4):1398-403.