"Receptor, trkB" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; neurotrophin 4 and neurotrophin 5. It is widely expressed in nervous tissue and plays a role in mediating the effects of neurotrophins on growth and differentiation of neuronal cells.
| Descriptor ID |
D020813
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.700 D12.776.543.750.630.498 D12.776.543.750.750.400.550.600
|
| Concept/Terms |
Receptor, trkB- Receptor, trkB
- BDNF Receptor
- Receptor, BDNF
- trkB Receptor
- Receptor, Neurotrophic Tyrosine Kinase Type 2
- NTRK2 Receptor
- Receptor, NTRK2
- Brain Derived Neurotrophic Factor Receptor
- Neurotrophic Tyrosine Kinase Receptor Type 2
- trkB(gp145) Protein
- Neurotrophic Factor, Brain-Derived, Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, trkB".
Below are MeSH descriptors whose meaning is more specific than "Receptor, trkB".
This graph shows the total number of publications written about "Receptor, trkB" by people in this website by year, and whether "Receptor, trkB" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, trkB" by people in Profiles.
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TrkB-mediated activation of the phosphatidylinositol-3-kinase/Akt cascade reduces the damage inflicted by oxygen-glucose deprivation in area CA3 of the rat hippocampus. Eur J Neurosci. 2018 05; 47(9):1096-1109.
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The role of leptin, melanocortin, and neurotrophin system genes on body weight in anorexia nervosa and bulimia nervosa. J Psychiatr Res. 2014 Aug; 55:77-86.
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Fingolimod phosphate attenuates oligomeric amyloid ß-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons. PLoS One. 2013; 8(4):e61988.
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Phase I trial of lestaurtinib for children with refractory neuroblastoma: a new approaches to neuroblastoma therapy consortium study. Cancer Chemother Pharmacol. 2011 Oct; 68(4):1057-65.