"Elafin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at high levels in SPUTUM. Elafin may play a role in the innate immunity (IMMUNITY, INNATE) response of the LUNG.
| Descriptor ID |
D053492
|
| MeSH Number(s) |
D12.644.822.437 D12.776.645.437
|
| Concept/Terms |
Elafin- Elafin
- Skin-Derived Antileukoproteinase
- Antileukoproteinase, Skin-Derived
- Skin Derived Antileukoproteinase
- Protease Inhibitor 3, Skin-derived
- Protease Inhibitor 3, Skin derived
- Protease Inhibitor WAP3
- Inhibitor WAP3, Protease
- Peptidase Inhibitor 3, Skin-derived
- Peptidase Inhibitor 3, Skin derived
|
Below are MeSH descriptors whose meaning is more general than "Elafin".
Below are MeSH descriptors whose meaning is more specific than "Elafin".
This graph shows the total number of publications written about "Elafin" by people in this website by year, and whether "Elafin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Elafin" by people in Profiles.
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Lifetime sexual violence exposure in women compromises systemic innate immune mediators associated with HIV pathogenesis: A cross-sectional analysis. Womens Health (Lond). 2022 Jan-Dec; 18:17455057221099486.
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Severe Pulmonary Arterial Hypertension Is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency. Chest. 2021 10; 160(4):1442-1458.
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Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition. Cancer Discov. 2014 Aug; 4(8):896-904.