Inducible T-Cell Co-Stimulator Protein
"Inducible T-Cell Co-Stimulator Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory receptor that is specific for INDUCIBLE T-CELL CO-STIMULATOR LIGAND. The receptor is associated with a diverse array of immunologically-related effects including the increased synthesis of INTERLEUKIN 10 in REGULATORY T-LYMPHOCYTES and the induction of PERIPHERAL TOLERANCE.
| Descriptor ID |
D060889
|
| MeSH Number(s) |
D12.776.543.750.705.222.812 D23.050.301.264.894.580 D23.101.100.894.580
|
| Concept/Terms |
Inducible T-Cell Co-Stimulator Protein- Inducible T-Cell Co-Stimulator Protein
- Inducible T Cell Co Stimulator Protein
- Inducible Co-Stimulator (ICOS)
- Inducible T-Cell Co-Stimulator
- Co-Stimulator, Inducible T-Cell
- Inducible T Cell Co Stimulator
- T-Cell Co-Stimulator, Inducible
- Antigens, CD278
- CD278 Antigens
- CD278 Antigen
- Antigen, CD278
- Activation-Inducible Lymphocyte Immunomediatory Molecule
- Activation Inducible Lymphocyte Immunomediatory Molecule
- Inducible Costimulator (ICOS)
- ICOS Inducible T-Cell Co-Stimulator
- ICOS Inducible T Cell Co Stimulator
|
Below are MeSH descriptors whose meaning is more general than "Inducible T-Cell Co-Stimulator Protein".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Costimulatory and Inhibitory T-Cell Receptors [D12.776.543.750.705.222]
- Inducible T-Cell Co-Stimulator Protein [D12.776.543.750.705.222.812]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- Inducible T-Cell Co-Stimulator Protein [D23.050.301.264.894.580]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- Inducible T-Cell Co-Stimulator Protein [D23.101.100.894.580]
Below are MeSH descriptors whose meaning is more specific than "Inducible T-Cell Co-Stimulator Protein".
This graph shows the total number of publications written about "Inducible T-Cell Co-Stimulator Protein" by people in this website by year, and whether "Inducible T-Cell Co-Stimulator Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2011 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Inducible T-Cell Co-Stimulator Protein" by people in Profiles.
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Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA. Nat Commun. 2018 01 19; 9(1):299.
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ICOS protects against mortality from acute lung injury through activation of IL-5+ ILC2s. Mucosal Immunol. 2018 01; 11(1):61-70.
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ICOS-expressing lymphocytes promote resolution of CD8-mediated lung injury in a mouse model of lung rejection. PLoS One. 2013; 8(8):e72955.
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Inducible costimulator controls migration of T cells to the lungs via down-regulation of CCR7 and CD62L. Am J Respir Cell Mol Biol. 2011 Oct; 45(4):843-50.
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Protective effector memory CD4 T cells depend on ICOS for survival. PLoS One. 2011 Feb 18; 6(2):e16529.
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Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cells. PLoS One. 2009 Nov 04; 4(11):e7525.
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CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo. Cell Immunol. 2009; 259(2):177-84.
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ICOS costimulation expands Th2 immunity by augmenting migration of lymphocytes to draining lymph nodes. J Immunol. 2008 Jul 15; 181(2):1019-24.
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Regulation of T:B cell interactions by the inducible costimulator molecule: does ICOS "induce" disease? Clin Immunol. 2006 Oct; 121(1):13-8.
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Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production. J Immunol. 2005 Aug 15; 175(4):2061-5.