"Thymine DNA Glycosylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that removes THYMINE and URACIL bases mispaired with GUANINE through hydrolysis of their N-glycosidic bond. These mispaired nucleotides generally occur through the hydrolytic DEAMINATION of 5-METHYLCYTOSINE to thymine.
| Descriptor ID |
D044502
|
| MeSH Number(s) |
D08.811.074.249.750 D08.811.277.450.430.099.750
|
| Concept/Terms |
Thymine DNA Glycosylase- Thymine DNA Glycosylase
- DNA Glycosylase, Thymine
- Glycosylase, Thymine DNA
- Thymine Glycol Glycosylase
- Glycol Glycosylase, Thymine
- Glycosylase, Thymine Glycol
- G-T Mismatch-Specific Thymine DNA Glycosylase
- G T Mismatch Specific Thymine DNA Glycosylase
- Thymine Glycol DNA Glycosylase
|
Below are MeSH descriptors whose meaning is more general than "Thymine DNA Glycosylase".
Below are MeSH descriptors whose meaning is more specific than "Thymine DNA Glycosylase".
This graph shows the total number of publications written about "Thymine DNA Glycosylase" by people in this website by year, and whether "Thymine DNA Glycosylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thymine DNA Glycosylase" by people in Profiles.
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Weakened N3 Hydrogen Bonding by 5-Formylcytosine and 5-Carboxylcytosine Reduces Their Base-Pairing Stability. ACS Chem Biol. 2016 Feb 19; 11(2):470-7.
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Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat Chem Biol. 2012 Feb 12; 8(4):328-30.