Signal Recognition Particle
"Signal Recognition Particle" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes associated with the rough endoplasmic reticulum. It consists of a 7S RNA and at least six polypeptide subunits (relative molecular masses 9, 14, 19, 54, 68, and 72K).
| Descriptor ID |
D018271
|
| MeSH Number(s) |
D12.776.157.725.500.750.800 D12.776.664.962.500.750.800
|
| Concept/Terms |
Signal Recognition Particle- Signal Recognition Particle
- Particle, Signal Recognition
- Recognition Particle, Signal
- SRP (Signal Recognition Particle)
|
Below are MeSH descriptors whose meaning is more general than "Signal Recognition Particle".
Below are MeSH descriptors whose meaning is more specific than "Signal Recognition Particle".
This graph shows the total number of publications written about "Signal Recognition Particle" by people in this website by year, and whether "Signal Recognition Particle" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Signal Recognition Particle" by people in Profiles.
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The mechanisms of integral membrane protein biogenesis. Nat Rev Mol Cell Biol. 2022 02; 23(2):107-124.
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A ribosome-associating factor chaperones tail-anchored membrane proteins. Nature. 2010 Aug 26; 466(7310):1120-4.
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The strange case of the signal recognition particle. Nat Rev Mol Cell Biol. 2002 07; 3(7):538-42.
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The signal recognition particle. Annu Rev Biochem. 2001; 70:755-75.
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Perspectives: structural biology. SRP--where the RNA and membrane worlds meet. Science. 2000 Feb 18; 287(5456):1212-3.
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Structure of the phylogenetically most conserved domain of SRP RNA. RNA. 1999 Nov; 5(11):1419-29.
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Type III machines of Gram-negative pathogens: injecting virulence factors into host cells and more. Curr Opin Microbiol. 1999 Feb; 2(1):18-24.
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Crystal structure of the signal sequence binding subunit of the signal recognition particle. Cell. 1998 Jul 24; 94(2):181-91.
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Structure of the conserved GTPase domain of the signal recognition particle. Nature. 1997 Jan 23; 385(6614):361-4.
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NMR studies of the most conserved RNA domain of the mammalian signal recognition particle (SRP). RNA. 1996 Dec; 2(12):1213-27.