"Heteroduplex Analysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A method of detecting gene mutation by mixing PCR-amplified mutant and wild-type DNA followed by denaturation and reannealing. The resultant products are resolved by gel electrophoresis, with single base substitutions detectable under optimal electrophoretic conditions and gel formulations. Large base pair mismatches may also be analyzed by using electron microscopy to visualize heteroduplex regions.
| Descriptor ID |
D020180
|
| MeSH Number(s) |
E05.393.661.250
|
| Concept/Terms |
Heteroduplex Analysis- Heteroduplex Analysis
- Analyses, Heteroduplex
- Analysis, Heteroduplex
- Heteroduplex Analyses
|
Below are MeSH descriptors whose meaning is more general than "Heteroduplex Analysis".
Below are MeSH descriptors whose meaning is more specific than "Heteroduplex Analysis".
This graph shows the total number of publications written about "Heteroduplex Analysis" by people in this website by year, and whether "Heteroduplex Analysis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Heteroduplex Analysis" by people in Profiles.
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Denaturing high-performance liquid chromatography for mutation detection and genotyping. Methods Mol Biol. 2013; 1015:25-54.