rap1 GTP-Binding Proteins
"rap1 GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetically related subfamily of RAP GTP-BINDING PROTEINS that share homology with RAS PROTEINS. They bind to Ras effectors but do not activate them, therefore they may antagonize the effects of RAS PROTEINS. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020827
|
| MeSH Number(s) |
D08.811.277.040.330.300.400.475.100 D12.644.360.525.475.100 D12.776.157.325.515.475.100 D12.776.476.525.475.100
|
| Concept/Terms |
rap1 GTP-Binding Protein- rap1 GTP-Binding Protein
- GTP-Binding Protein, rap1
- rap1 GTP Binding Protein
- rap1A Protein
- smg p21 GTP-Binding Protein
- smg p21 GTP Binding Protein
- smg p21A Protein
- p21A Protein, smg
- rap1A GTP-Binding Protein
- GTP-Binding Protein, rap1A
- rap1A GTP Binding Protein
- Krev-1 GTP-Binding Protein
- GTP-Binding Protein, Krev-1
- Krev 1 GTP Binding Protein
- SMG p21A GTP-Binding Protein
- SMG p21A GTP Binding Protein
- Krev-1 Protein
- Krev 1 Protein
|
Below are MeSH descriptors whose meaning is more general than "rap1 GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "rap1 GTP-Binding Proteins".
This graph shows the total number of publications written about "rap1 GTP-Binding Proteins" by people in this website by year, and whether "rap1 GTP-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2012 | 1 | 1 | 2 |
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Below are the most recent publications written about "rap1 GTP-Binding Proteins" by people in Profiles.
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Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1. Biochim Biophys Acta. 2015 May; 1852(5):778-91.
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Rap-afadin axis in control of Rho signaling and endothelial barrier recovery. Mol Biol Cell. 2013 Sep; 24(17):2678-88.
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A novel interplay between Rap1 and PKA regulates induction of angiogenesis in prostate cancer. PLoS One. 2012; 7(11):e49893.
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Afadin controls p120-catenin-ZO-1 interactions leading to endothelial barrier enhancement by oxidized phospholipids. J Cell Physiol. 2012 May; 227(5):1883-90.
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Rap1 mediates protective effects of iloprost against ventilator-induced lung injury. J Appl Physiol (1985). 2009 Dec; 107(6):1900-10.
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A novel interplay between Epac/Rap1 and mitogen-activated protein kinase kinase 5/extracellular signal-regulated kinase 5 (MEK5/ERK5) regulates thrombospondin to control angiogenesis. Blood. 2009 Nov 12; 114(20):4592-600.
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Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Curr Biol. 2004 Apr 06; 14(7):606-10.
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The CrkL adapter protein is required for type I interferon-dependent gene transcription and activation of the small G-protein Rap1. Biochem Biophys Res Commun. 2002 Mar 08; 291(4):744-50.
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Focal adhesions require catalytic activity of Src family kinases to mediate integrin-matrix adhesion. Mol Cell Biol. 2002 Feb; 22(4):1203-17.
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Rap1 is involved in cell stretching modulation of p38 but not ERK or JNK MAP kinase. J Cell Sci. 2001 Mar; 114(Pt 6):1221-7.