Ikaros Transcription Factor
"Ikaros Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that plays a role as a key regulator of HEMATOPOIESIS. Aberrant Ikaros expression has been associated with LYMPHOBLASTIC LEUKEMIA.
| Descriptor ID |
D051740
|
| MeSH Number(s) |
D12.776.260.522.500 D12.776.930.375.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ikaros Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "Ikaros Transcription Factor".
This graph shows the total number of publications written about "Ikaros Transcription Factor" by people in this website by year, and whether "Ikaros Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 3 | 0 | 3 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 4 | 2 | 6 |
| 2014 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Ikaros Transcription Factor" by people in Profiles.
-
Chromatin Protein PC4 Orchestrates B Cell Differentiation by Collaborating with IKAROS and IRF4. Cell Rep. 2020 12 22; 33(12):108517.
-
B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. Cell. 2018 04 05; 173(2):470-484.e18.
-
Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia. Genes Dev. 2016 09 01; 30(17):1971-90.
-
Clinical impact of ABL1 kinase domain mutations and IKZF1 deletion in adults under age 60 with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL): molecular analysis of CALGB (Alliance) 10001 and 9665. Leuk Lymphoma. 2016 10; 57(10):2298-306.
-
Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study. J Allergy Clin Immunol. 2014 Aug; 134(2):295-305.
-
Fingerprinting ikaros. Nat Immunol. 2013 Oct; 14(10):1034-5.
-
Transcriptional regulation of the Ikzf1 locus. Blood. 2013 Oct 31; 122(18):3149-59.
-
Ikaros limits basophil development by suppressing C/EBP-a expression. Blood. 2013 Oct 10; 122(15):2572-81.
-
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst. 2013 May 15; 105(10):733-42.
-
FoxP3, Helios, and SATB1: roles and relationships in regulatory T cells. Int Immunopharmacol. 2013 Jul; 16(3):343-7.