"Podophyllotoxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.
| Descriptor ID |
D011034
|
| MeSH Number(s) |
D02.455.426.559.389.140.450.777 D02.455.426.559.847.638.960.675 D04.615.638.960.675
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Podophyllotoxin".
Below are MeSH descriptors whose meaning is more specific than "Podophyllotoxin".
This graph shows the total number of publications written about "Podophyllotoxin" by people in this website by year, and whether "Podophyllotoxin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Podophyllotoxin" by people in Profiles.
-
Secondary acute myelogenous leukemia in patients with retinoblastoma: is chemotherapy a factor? Ophthalmology. 2007 Jul; 114(7):1378-83.
-
Carmustine, etoposide, cytarabine and melphalan as a preparative regimen for allogeneic transplantation for high-risk malignant lymphoma. Ann Oncol. 1999 May; 10(5):527-32.
-
Pharmacodynamics and long-term toxicity of etoposide. Cancer Chemother Pharmacol. 1994; 34 Suppl:S64-8.
-
New perspectives on the toxicity of etoposide. Semin Oncol. 1992 Dec; 19(6 Suppl 13):78-83.
-
Therapy-related acute myeloid leukemia secondary to inhibitors of topoisomerase II: from the bedside to the target genes. Ann Oncol. 1992 Feb; 3(2):107-11.
-
Patient-applied podofilox for treatment of genital warts. Lancet. 1989 Apr 15; 1(8642):831-4.
-
Phase II trial of teniposide in previously treated and untreated patients with advanced colorectal carcinoma: an Illinois Cancer Council Trial. Cancer Treat Rep. 1986 Feb; 70(2):307-8.
-
VP16-213 in combined modality treatment of small cell carcinoma of the lung. Eur J Cancer Clin Oncol. 1982 Apr; 18(4):343-6.
-
Phase II evaluation of VM-26 in patients with metastatic transitional cell carcinoma of the urinary tract: an Eastern Cooperative Oncology Group study. Cancer Treat Rep. 1982 Feb; 66(2):405-6.
-
Treatment of grade III and IV astrocytomas with BCNU alone and in combination with VM-26 following surgery and radiation therapy. Cancer Treat Rep. 1979 Nov-Dec; 63(11-12):1707-11.