8-Hydroxy-2-(di-n-propylamino)tetralin
"8-Hydroxy-2-(di-n-propylamino)tetralin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
Descriptor ID |
D017371
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MeSH Number(s) |
D02.455.426.559.847.638.960.400 D04.615.638.960.400
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "8-Hydroxy-2-(di-n-propylamino)tetralin".
Below are MeSH descriptors whose meaning is more specific than "8-Hydroxy-2-(di-n-propylamino)tetralin".
This graph shows the total number of publications written about "8-Hydroxy-2-(di-n-propylamino)tetralin" by people in this website by year, and whether "8-Hydroxy-2-(di-n-propylamino)tetralin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "8-Hydroxy-2-(di-n-propylamino)tetralin" by people in Profiles.
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Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice. Biol Psychiatry. 2011 Dec 01; 70(11):1039-48.
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Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice. Biol Psychiatry. 2009 Mar 01; 65(5):401-8.
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Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science. 2003 Aug 08; 301(5634):805-9.
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Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition. Neuropsychopharmacology. 2000 Jun; 22(6):650-9.
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Serotonin1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin1B knockout mice. Psychopharmacology (Berl). 1997 Jul; 132(2):125-34.
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Hyperammonemia increases serotonin 1A receptor expression in both rat hippocampus and a transfected hippocampal cell line, HN2-5. J Neurosci Res. 1995 May 01; 41(1):105-10.
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Differential solubilization of membrane lipids by detergents: coenrichment of the sheep brain serotonin 5-HT1A receptor with phospholipids containing predominantly saturated fatty acids. Arch Biochem Biophys. 1993 Aug 15; 305(1):68-77.
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Heterologous expression of the serotonin 5-HT1A receptor in neural and non-neural cell lines. Biochem Biophys Res Commun. 1993 Apr 15; 192(1):104-10.
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8-hydroxy-2-(di-n-propylamino)tetralin-responsive 5-hydroxytryptamine4-like receptor expressed in bovine pulmonary artery smooth muscle cells. Mol Pharmacol. 1992 Nov; 42(5):817-25.
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Enrichment of saturated fatty acid containing phospholipids in sheep brain serotonin receptor preparations: use of microwave irradiation for rapid transesterification of phospholipids. Biochim Biophys Acta. 1992 Sep 21; 1110(1):65-74.