"Serine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
| Descriptor ID |
D012694
|
| MeSH Number(s) |
D12.125.154.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Serine".
Below are MeSH descriptors whose meaning is more specific than "Serine".
This graph shows the total number of publications written about "Serine" by people in this website by year, and whether "Serine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 4 | 4 |
| 2004 | 1 | 3 | 4 |
| 2005 | 1 | 7 | 8 |
| 2006 | 1 | 4 | 5 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 3 | 4 |
| 2010 | 2 | 2 | 4 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 2 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 3 | 0 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 3 | 3 |
| 2019 | 2 | 1 | 3 |
| 2020 | 2 | 2 | 4 |
| 2022 | 2 | 1 | 3 |
| 2024 | 1 | 2 | 3 |
| 2025 | 2 | 2 | 4 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serine" by people in Profiles.
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In vitro properties of large serine integrase hybrids derived from ?C31 and TG1 integrases. Nucleic Acids Res. 2026 Jul 17; 54(14).
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Now you serine, now you don't. Trends Pharmacol Sci. 2025 11; 46(11):1047-1048.
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Enhancing cardiac serine biosynthesis mitigates the progression of dilated cardiomyopathy in mice. Metabolism. 2026 01; 174:156395.
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Identification of cognate recombination directionality factors for large serine recombinases by virtual pulldown. Nucleic Acids Res. 2025 Jul 19; 53(14).
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Large serine integrases utilise scavenged phage proteins as directionality cofactors. Nucleic Acids Res. 2025 01 24; 53(3).
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Variable orthogonality of serine integrase interactions within the ?C31 family. Sci Rep. 2024 11 01; 14(1):26280.
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A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nat Biomed Eng. 2024 May; 8(5):611-627.
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Mendelian Randomization Study With Clinical Follow-Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension. J Am Heart Assoc. 2024 03 19; 13(6):e032256.
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Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy. Eur Heart J. 2022 09 21; 43(36):3477-3489.
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Serine 408 phosphorylation is a molecular switch that regulates structure and function of the occludin a-helical bundle. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2204618119.