"Azaserine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antibiotic substance produced by various Streptomyces species. It is an inhibitor of enzymatic activities that involve glutamine and is used as an antineoplastic and immunosuppressive agent.
| Descriptor ID |
D001377
|
| MeSH Number(s) |
D12.125.154.800.500
|
| Concept/Terms |
Azaserine- Azaserine
- O-Diazoacetyl-L-serine
- O Diazoacetyl L serine
- Azeserine
|
Below are MeSH descriptors whose meaning is more general than "Azaserine".
Below are MeSH descriptors whose meaning is more specific than "Azaserine".
This graph shows the total number of publications written about "Azaserine" by people in this website by year, and whether "Azaserine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Azaserine" by people in Profiles.
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The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer. Nat Metab. 2020 12; 2(12):1401-1412.
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Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis. Mol Pharmacol. 1997 Nov; 52(5):903-11.
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Regulation of purine synthesis de novo in human fibroblasts by purine nucleotides and phosphoribosylpyrophosphate. J Biol Chem. 1987 Oct 25; 262(30):14531-7.
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Effects of nicotinic acid on human fibroblast purine biosynthesis. Biochim Biophys Acta. 1972 May 10; 269(2):179-83.