"Substance P" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
| Descriptor ID |
D013373
|
| MeSH Number(s) |
D12.644.276.812.900.866 D12.644.400.800.750 D12.644.456.800.866 D12.776.467.812.900.866 D12.776.631.650.800.750 D23.469.050.375.850.890 D23.529.812.900.866
|
| Concept/Terms |
Substance P- Substance P
- Euler-Gaddum Substance P
- Euler Gaddum Substance P
- Substance P, Euler-Gaddum
- SP(1-11)
|
Below are MeSH descriptors whose meaning is more general than "Substance P".
Below are MeSH descriptors whose meaning is more specific than "Substance P".
This graph shows the total number of publications written about "Substance P" by people in this website by year, and whether "Substance P" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 3 | 1 | 4 |
| 1997 | 2 | 0 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 0 | 2 |
| 2001 | 3 | 1 | 4 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Substance P" by people in Profiles.
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Insights into the dynamic control of breathing revealed through cell-type-specific responses to substance P. Elife. 2019 12 05; 8.
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Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult. J Diabetes Res. 2019; 2019:9426014.
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Design, Synthesis, and Evaluation of a Diazirine Photoaffinity Probe for Ligand-Based Receptor Capture Targeting G Protein-Coupled Receptors. Mol Pharmacol. 2019 02; 95(2):196-209.
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Substance P and neurokinin 1 receptors as potential therapeutic targets in children with OSA. Chest. 2014 May; 145(5):1039-1045.
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Defining modulatory inputs into CNS neuronal subclasses by functional pharmacological profiling. Proc Natl Acad Sci U S A. 2014 Apr 29; 111(17):6449-54.
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Cerebrospinal fluid substance P-like immunoreactivity correlates with aggression in personality disordered subjects. Biol Psychiatry. 2012 Aug 01; 72(3):238-43.
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Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo. Bioconjug Chem. 2012 Jan 18; 23(1):42-6.
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Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase. J Appl Physiol (1985). 2011 Oct; 111(4):964-70.
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Substance P modulation of TRPC3/7 channels improves respiratory rhythm regularity and ICAN-dependent pacemaker activity. Eur J Neurosci. 2010 Apr; 31(7):1219-32.
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An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):11011-5.