"Cathepsin K" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme.
| Descriptor ID |
D056657
|
| MeSH Number(s) |
D08.811.277.656.224.405 D08.811.277.656.262.500.156 D08.811.277.656.300.200.156
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cathepsin K".
Below are MeSH descriptors whose meaning is more specific than "Cathepsin K".
This graph shows the total number of publications written about "Cathepsin K" by people in this website by year, and whether "Cathepsin K" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cathepsin K" by people in Profiles.
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A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods. Nat Commun. 2014; 5:3287.
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A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies. PLoS Med. 2006 Dec; 3(12):e486.
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Cathepsin protease activity modulates amyloid load in extracerebral amyloidosis. J Pathol. 2006 Dec; 210(4):478-87.