Inhibitor of Differentiation Protein 2
"Inhibitor of Differentiation Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negative regulator of BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS. It plays a role in regulating IMMUNOGLOBULIN E expression.
| Descriptor ID |
D051797
|
| MeSH Number(s) |
D12.776.930.329.500
|
| Concept/Terms |
Inhibitor of Differentiation Protein 2- Inhibitor of Differentiation Protein 2
- Inhibitor of DNA Binding 2 Protein
- DNA-Binding Protein Inhibitor ID-2
- DNA Binding Protein Inhibitor ID 2
- Inhibitor of Differentiation 2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Inhibitor of Differentiation Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Inhibitor of Differentiation Protein 2".
This graph shows the total number of publications written about "Inhibitor of Differentiation Protein 2" by people in this website by year, and whether "Inhibitor of Differentiation Protein 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2007 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Inhibitor of Differentiation Protein 2" by people in Profiles.
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The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude. J Exp Med. 2021 06 07; 218(6).
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Transcription factor ID2 prevents E proteins from enforcing a naïve T lymphocyte gene program during NK cell development. Sci Immunol. 2018 04 27; 3(22).
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Murine thymic NK cells are distinct from ILC1s and have unique transcription factor requirements. Eur J Immunol. 2017 05; 47(5):800-805.
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The ETS1 transcription factor is required for the development and cytokine-induced expansion of ILC2. J Exp Med. 2016 05 02; 213(5):687-96.
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Innate Lymphoid Cells Control Early Colonization Resistance against Intestinal Pathogens through ID2-Dependent Regulation of the Microbiota. Immunity. 2015 Apr 21; 42(4):731-43.
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A committed precursor to innate lymphoid cells. Nature. 2014 Apr 17; 508(7496):397-401.
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Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development. J Immunol. 2013 Dec 15; 191(12):5973-83.
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Inhibitors of DNA binding proteins restrict T cell potential by repressing Notch1 expression in Flt3-negative common lymphoid progenitors. J Immunol. 2012 Oct 15; 189(8):3822-30.
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Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1. Immunity. 2012 Jun 29; 36(6):921-32.
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Multiple hats for natural killers. Curr Opin Immunol. 2010 Apr; 22(2):193-8.