"4-Nitroquinoline-1-oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but not bacteriophage.
| Descriptor ID |
D015112
|
| MeSH Number(s) |
D02.640.820.600 D03.633.100.810.470.450 D03.661.243.500
|
| Concept/Terms |
4-Nitroquinoline-1-oxide- 4-Nitroquinoline-1-oxide
- 4 Nitroquinoline 1 oxide
- 4-Nitroquinoline-N-oxide
- 4 Nitroquinoline N oxide
|
Below are MeSH descriptors whose meaning is more general than "4-Nitroquinoline-1-oxide".
Below are MeSH descriptors whose meaning is more specific than "4-Nitroquinoline-1-oxide".
This graph shows the total number of publications written about "4-Nitroquinoline-1-oxide" by people in this website by year, and whether "4-Nitroquinoline-1-oxide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "4-Nitroquinoline-1-oxide" by people in Profiles.
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Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma. Cell Rep Med. 2021 09 21; 2(9):100399.
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Met Receptor Tyrosine Kinase and Chemoprevention of Oral Cancer. J Natl Cancer Inst. 2018 03 01; 110(3).
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Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis. Cancer Res. 2015 Sep 15; 75(18):3958-3969.
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PTEN deficiency contributes to the development and progression of head and neck cancer. Neoplasia. 2013 May; 15(5):461-71.
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Topical polyethylene glycol as a novel chemopreventive agent for oral cancer via targeting of epidermal growth factor response. PLoS One. 2012; 7(6):e38047.
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Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma. Cancer Prev Res (Phila). 2011 Feb; 4(2):230-7.
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Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis. Cancer Prev Res (Phila). 2010 Nov; 3(11):1493-502.
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ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis. Cancer Prev Res (Phila). 2009 Apr; 2(4):385-93.
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4-nitroquinoline-1-oxide induced experimental oral carcinogenesis. Oral Oncol. 2006 Aug; 42(7):655-67.