"Heparin Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the isomerase class that catalyzes the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. (From Enzyme Nomenclature, 1992) EC 4.2.2.7.
| Descriptor ID |
D019763
|
| MeSH Number(s) |
D08.811.520.241.700.512
|
| Concept/Terms |
Heparin Lyase- Heparin Lyase
- Lyase, Heparin
- Neutralase
- Heparinase I
- Heparin Eliminase
- Eliminase, Heparin
- Heparinase
|
Below are MeSH descriptors whose meaning is more general than "Heparin Lyase".
Below are MeSH descriptors whose meaning is more specific than "Heparin Lyase".
This graph shows the total number of publications written about "Heparin Lyase" by people in this website by year, and whether "Heparin Lyase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1999 | 1 | 1 | 2 |
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Below are the most recent publications written about "Heparin Lyase" by people in Profiles.
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'Immunosequencing' of heparan sulfate from human cell lines and rat kidney: the (GlcNS6S-IdoA2S)3 motif, recognized by antibody NS4F5, is located towards the non-reducing end. Biochem J. 2014 Aug 01; 461(3):461-8.
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Ex vivo reversal of heparin-mediated cardioprotection by heparinase after ischemia and reperfusion. J Pharmacol Exp Ther. 1999 Sep; 290(3):1041-7.
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Peptide model of a highly conserved, N-terminal domain of apolipoprotein E is able to modulate lipoprotein binding to a member of the class A scavenger receptor family. J Lipid Res. 1999 Apr; 40(4):753-63.
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Conformationally specific enhancement of receptor-mediated LDL binding and internalization by peptide models of a conserved anionic N-terminal domain of human apolipoprotein E. Biochemistry. 1996 Nov 05; 35(44):13975-84.
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Amphiregulin in lung branching morphogenesis: interaction with heparan sulfate proteoglycan modulates cell proliferation. Development. 1996 Jun; 122(6):1759-67.