"Proto-Oncogene Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.
Descriptor ID |
D011518
|
MeSH Number(s) |
D12.776.624.664.700
|
Concept/Terms |
Proto-Oncogene Proteins- Proto-Oncogene Proteins
- Proto Oncogene Proteins
- Proto-Oncogene Products, Cellular
- Cellular Proto-Oncogene Products
- Proto Oncogene Products, Cellular
- Proto Oncogene Proteins, Cellular
- c-onc Proteins
- c onc Proteins
- Cellular Proto-Oncogene Proteins
- Cellular Proto Oncogene Proteins
- Proto-Oncogene Proteins, Cellular
|
Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins".
This graph shows the total number of publications written about "Proto-Oncogene Proteins" by people in this website by year, and whether "Proto-Oncogene Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 11 | 4 | 15 |
1995 | 14 | 6 | 20 |
1996 | 11 | 4 | 15 |
1997 | 11 | 9 | 20 |
1998 | 5 | 3 | 8 |
1999 | 7 | 6 | 13 |
2000 | 8 | 8 | 16 |
2001 | 8 | 11 | 19 |
2002 | 18 | 19 | 37 |
2003 | 13 | 16 | 29 |
2004 | 24 | 11 | 35 |
2005 | 4 | 6 | 10 |
2006 | 3 | 6 | 9 |
2007 | 7 | 2 | 9 |
2008 | 6 | 6 | 12 |
2009 | 10 | 2 | 12 |
2010 | 11 | 13 | 24 |
2011 | 10 | 6 | 16 |
2012 | 13 | 10 | 23 |
2013 | 12 | 8 | 20 |
2014 | 16 | 5 | 21 |
2015 | 18 | 2 | 20 |
2016 | 4 | 6 | 10 |
2017 | 2 | 3 | 5 |
2018 | 6 | 7 | 13 |
2019 | 8 | 2 | 10 |
2020 | 5 | 2 | 7 |
2021 | 3 | 6 | 9 |
2022 | 4 | 2 | 6 |
2023 | 2 | 3 | 5 |
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Below are the most recent publications written about "Proto-Oncogene Proteins" by people in Profiles.
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Single-nucleus DNA sequencing reveals hidden somatic loss-of-heterozygosity in Cerebral Cavernous Malformations. Nat Commun. 2023 11 02; 14(1):7009.
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Ratiometric sensing of Pnt and Yan transcription factor levels confers ultrasensitivity to photoreceptor fate transitions in Drosophila. Development. 2023 04 15; 150(8).
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Dual Axl/MerTK inhibitor INCB081776 creates a proinflammatory tumor immune microenvironment and enhances anti-PDL1 efficacy in head and neck cancer. Head Neck. 2023 05; 45(5):1255-1271.
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The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia. Nature. 2023 03; 615(7954):920-924.
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TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype. Gastroenterology. 2023 05; 164(6):921-936.e1.
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PU.1-Dependent Enhancer Inhibition Separates Tet2-Deficient Hematopoiesis from Malignant Transformation. Blood Cancer Discov. 2022 09 06; 3(5):444-467.
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MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia. Epigenetics. 2022 12; 17(13):2056-2074.
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AXL regulates neuregulin1 expression leading to cetuximab resistance in head and neck cancer. BMC Cancer. 2022 Apr 23; 22(1):447.
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Loss of MEN1 function impairs DNA repair capability of pancreatic neuroendocrine tumors. Endocr Relat Cancer. 2022 03 21; 29(4):225-239.
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A WIN Consortium phase I study exploring avelumab, palbociclib, and axitinib in advanced non-small cell lung cancer. Cancer Med. 2022 07; 11(14):2790-2800.