"Fatty Acid Desaturases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of enzymes that catalyze the stereoselective, regioselective, or chemoselective syn-dehydrogenation reactions. They function by a mechanism that is linked directly to reduction of molecular OXYGEN.
| Descriptor ID |
D044943
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| MeSH Number(s) |
D08.811.682.690.708.392
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fatty Acid Desaturases".
Below are MeSH descriptors whose meaning is more specific than "Fatty Acid Desaturases".
This graph shows the total number of publications written about "Fatty Acid Desaturases" by people in this website by year, and whether "Fatty Acid Desaturases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fatty Acid Desaturases" by people in Profiles.
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Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity. Nature. 2019 02; 566(7744):403-406.
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Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-?-linolenic acid peroxidation dependent mechanism. BMC Cancer. 2018 03 27; 18(1):330.
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A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes. J Allergy Clin Immunol. 2014 Nov; 134(5):1153-62.
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Omega-3 fatty acids: new insights into the pharmacology and biology of docosahexaenoic acid, docosapentaenoic acid, and eicosapentaenoic acid. Curr Opin Lipidol. 2013 Dec; 24(6):467-74.
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Adaptive evolution of the FADS gene cluster within Africa. PLoS One. 2012; 7(9):e44926.
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Proper control of genetic background with precise allele substitution: a comment on Coyne and Elwyn. Evolution. 2006 Mar; 60(3):623-5; discussion 626-7.
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Does the desaturase-2 locus in Drosophila melanogaster cause adaptation and sexual isolation? Evolution. 2006 Feb; 60(2):279-91.
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Adaptive loss of an old duplicated gene during incipient speciation. Mol Biol Evol. 2006 Feb; 23(2):401-10.
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Ecological adaptation during incipient speciation revealed by precise gene replacement. Science. 2003 Dec 05; 302(5651):1754-7.
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TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells. Blood. 2003 May 01; 101(9):3658-67.