Phenylalanine Hydroxylase
"Phenylalanine Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the oxidoreductase class that catalyzes the formation of L-TYROSINE, dihydrobiopterin, and water from L-PHENYLALANINE, tetrahydrobiopterin, and oxygen. Deficiency of this enzyme may cause PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL. EC 1.14.16.1.
| Descriptor ID |
D010651
|
| MeSH Number(s) |
D08.811.682.690.708.601
|
| Concept/Terms |
Phenylalanine Hydroxylase- Phenylalanine Hydroxylase
- Hydroxylase, Phenylalanine
- Phenylalanine 4-Hydroxylase
- 4-Hydroxylase, Phenylalanine
- Phenylalanine 4 Hydroxylase
- Phenylalanine 4-Monooxygenase
- 4-Monooxygenase, Phenylalanine
- Phenylalanine 4 Monooxygenase
|
Below are MeSH descriptors whose meaning is more general than "Phenylalanine Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Phenylalanine Hydroxylase".
This graph shows the total number of publications written about "Phenylalanine Hydroxylase" by people in this website by year, and whether "Phenylalanine Hydroxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phenylalanine Hydroxylase" by people in Profiles.
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A porcine model of phenylketonuria generated by CRISPR/Cas9 genome editing. JCI Insight. 2020 10 15; 5(20).
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Unique aspects of sequence variant interpretation for inborn errors of metabolism (IEM): The ClinGen IEM Working Group and the Phenylalanine Hydroxylase Gene. Hum Mutat. 2018 11; 39(11):1569-1580.
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Kinetics of tetrahydrobiopterin synthesis by rabbit brain dihydrofolate reductase. Biochem J. 1978 Apr 01; 171(1):267-8.