Long-Term Synaptic Depression
"Long-Term Synaptic Depression" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY.
Descriptor ID |
D036881
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MeSH Number(s) |
G11.561.638.355
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Concept/Terms |
Long-Term Synaptic Depression- Long-Term Synaptic Depression
- Long Term Synaptic Depression
- Synaptic Depression, Long-Term
- Long-Term Depression, Physiological
- Depression, Physiological Long-Term
- Depressions, Physiological Long-Term
- Long Term Depression, Physiological
- Long-Term Depressions, Physiological
- Physiological Long-Term Depression
- Physiological Long-Term Depressions
- Long-Term Depression, Neurophysiological
- Depression, Neurophysiological Long-Term
- Depressions, Neurophysiological Long-Term
- Long Term Depression, Neurophysiological
- Long-Term Depressions, Neurophysiological
- Neurophysiological Long-Term Depression
- Neurophysiological Long-Term Depressions
- Long-Term Depression, Physiologic
- Long Term Depression, Physiologic
- Physiologic Long-Term Depression
- Long-Term Depression, Neurophysiologic
- Long Term Depression, Neurophysiologic
- Neurophysiologic Long-Term Depression
Depotentiation- Depotentiation
- Homosynaptic Depression
- Depression, Homosynaptic
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Below are MeSH descriptors whose meaning is more general than "Long-Term Synaptic Depression".
Below are MeSH descriptors whose meaning is more specific than "Long-Term Synaptic Depression".
This graph shows the total number of publications written about "Long-Term Synaptic Depression" by people in this website by year, and whether "Long-Term Synaptic Depression" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2005 | 2 | 0 | 2 |
2006 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2009 | 0 | 1 | 1 |
2010 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Long-Term Synaptic Depression" by people in Profiles.
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Deregulation of synaptic plasticity in autism. Neurosci Lett. 2019 01 01; 688:58-61.
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Metabotropic glutamate receptor 2 inhibits thalamically-driven glutamate and dopamine release in the dorsal striatum. Neuropharmacology. 2017 05 01; 117:114-123.
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LTD-like molecular pathways in developmental synaptic pruning. Nat Neurosci. 2016 09 27; 19(10):1299-310.
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Enhanced AMPA receptor function promotes cerebellar long-term depression rather than potentiation. Learn Mem. 2014 Dec; 21(12):662-7.
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Chronic alcohol alters rewarded behaviors and striatal plasticity. Addict Biol. 2015 Mar; 20(2):345-8.
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Opioids induce dissociable forms of long-term depression of excitatory inputs to the dorsal striatum. Nat Neurosci. 2014 Apr; 17(4):540-8.
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Chronic methylphenidate exposure during adolescence reduces striatal synaptic responses to ethanol. Eur J Neurosci. 2014 Feb; 39(4):548-56.
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Ethanol affects NMDA receptor signaling at climbing fiber-Purkinje cell synapses in mice and impairs cerebellar LTD. J Neurophysiol. 2013 Mar; 109(5):1333-42.
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Endocannabinoids in striatal plasticity. Parkinsonism Relat Disord. 2012 Jan; 18 Suppl 1:S132-4.
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An anticholinergic reverses motor control and corticostriatal LTD deficits in Dyt1 ?GAG knock-in mice. Behav Brain Res. 2012 Jan 15; 226(2):465-72.