Small-Conductance Calcium-Activated Potassium Channels
"Small-Conductance Calcium-Activated Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major class of calcium-activated potassium channels that are found primarily in excitable CELLS. They play important roles in the transmission of ACTION POTENTIALS and generate a long-lasting hyperpolarization known as the slow afterhyperpolarization.
| Descriptor ID |
D051640
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| MeSH Number(s) |
D12.776.157.530.400.600.150.750 D12.776.543.550.450.750.150.750 D12.776.543.585.400.750.150.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Small-Conductance Calcium-Activated Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Small-Conductance Calcium-Activated Potassium Channels".
This graph shows the total number of publications written about "Small-Conductance Calcium-Activated Potassium Channels" by people in this website by year, and whether "Small-Conductance Calcium-Activated Potassium Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2020 | 3 | 1 | 4 |
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Below are the most recent publications written about "Small-Conductance Calcium-Activated Potassium Channels" by people in Profiles.
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Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders. Brain. 2020 12 01; 143(12):3564-3573.
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Muscarinic Modulation of SK2-Type K+ Channels Promotes Intrinsic Plasticity in L2/3 Pyramidal Neurons of the Mouse Primary Somatosensory Cortex. eNeuro. 2020 Mar/Apr; 7(2).
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Intrinsic Excitability Increase in Cerebellar Purkinje Cells after Delay Eye-Blink Conditioning in Mice. J Neurosci. 2020 03 04; 40(10):2038-2046.
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SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning-specific memory traces. PLoS Biol. 2020 01; 18(1):e3000596.
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Activity-Dependent Plasticity of Spike Pauses in Cerebellar Purkinje Cells. Cell Rep. 2016 Mar 22; 14(11):2546-53.
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SK2 channel modulation contributes to compartment-specific dendritic plasticity in cerebellar Purkinje cells. Neuron. 2012 Jul 12; 75(1):108-20.
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Dopamine neurons in the ventral tegmental area fire faster in adolescent rats than in adults. J Neurophysiol. 2012 Sep; 108(6):1620-30.
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Ataxias and cerebellar dysfunction: involvement of synaptic plasticity deficits? Funct Neurol. 2010 Jul-Sep; 25(3):135-9.
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Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses. Diabetes. 2003 Aug; 52(8):2000-6.
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Giant excised patch recordings of recombinant ion channel currents expressed in mammalian cells. Neurosci Lett. 2002 Aug 23; 329(1):17-20.