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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. Proc Natl Acad Sci U S A. 2010 May 11; 107(19):8788-93.
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PubMed
subject areas
Aerobiosis
Animals
Cell Adhesion
Cell Proliferation
Cell Transformation, Neoplastic
Electron Transport Complex III
Extracellular Signal-Regulated MAP Kinases
Glutamine
Glycolysis
HCT116 Cells
Humans
Lung Neoplasms
Mice
Mitochondria
Oxidative Phosphorylation
Pentose Phosphate Pathway
Proto-Oncogene Proteins p21(ras)
Reactive Oxygen Species
authors with profiles
Gokhan M. Mutlu
Robert Hamanaka