"Kruppel-Like Factor 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Kruppel-like transcription factor that contains three C-terminal CYS2-HIS2 ZINC FINGERS and binds to GC RICH SEQUENCE (GC box) in upstream gene promoters. It functions as a transcriptional activator, tumor suppressor, and may regulate growth and development of B-cells.
Descriptor ID |
D000075723
|
MeSH Number(s) |
D12.776.260.522.563 D12.776.260.755.050 D12.776.624.664.700.120 D12.776.930.375.563
|
Concept/Terms |
Kruppel-Like Factor 6- Kruppel-Like Factor 6
- Kruppel Like Factor 6
- CPBP Protein
- Core Promoter Element Binding Protein
- COPEB Protein
|
Below are MeSH descriptors whose meaning is more general than "Kruppel-Like Factor 6".
Below are MeSH descriptors whose meaning is more specific than "Kruppel-Like Factor 6".
This graph shows the total number of publications written about "Kruppel-Like Factor 6" by people in this website by year, and whether "Kruppel-Like Factor 6" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Kruppel-Like Factor 6" by people in Profiles.
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A genome-wide genetic screen uncovers determinants of human pigmentation. Science. 2023 08 11; 381(6658):eade6289.
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SP1-induced long non-coding RNA SNHG6 facilitates the carcinogenesis of chondrosarcoma through inhibiting KLF6 by recruiting EZH2. Cell Death Dis. 2021 01 11; 12(1):59.
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KLF6 contributes to myeloid cell plasticity in the pathogenesis of intestinal inflammation. Mucosal Immunol. 2016 09; 9(5):1250-62.
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Aberrant RNA splicing and its functional consequences in cancer cells. Dis Model Mech. 2008 Jul-Aug; 1(1):37-42.