"X-Box Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in the promoter region. It regulates the expression of genes involved in the UNFOLDED PROTEIN RESPONSE.
| Descriptor ID |
D000071717
|
| MeSH Number(s) |
D12.776.260.108.937 D12.776.930.127.937
|
| Concept/Terms |
X-Box Binding Protein 1- X-Box Binding Protein 1
- X Box Binding Protein 1
- TREB5 Protein
- Tax-Responsive Element-Binding Protein 5
- Tax Responsive Element Binding Protein 5
- XBP-1 Protein
- XBP 1 Protein
- TREB-5 Protein
- TREB 5 Protein
- XBP2 Protein
|
Below are MeSH descriptors whose meaning is more general than "X-Box Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "X-Box Binding Protein 1".
This graph shows the total number of publications written about "X-Box Binding Protein 1" by people in this website by year, and whether "X-Box Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 1 | 2 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "X-Box Binding Protein 1" by people in Profiles.
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SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1a/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells. mBio. 2022 10 26; 13(5):e0241522.
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Type I but Not Type II Calreticulin Mutations Activate the IRE1a/XBP1 Pathway of the Unfolded Protein Response to Drive Myeloproliferative Neoplasms. Blood Cancer Discov. 2022 07 06; 3(4):298-315.
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Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Mol Cancer Ther. 2021 01; 20(1):11-25.
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Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR. Cell. 2019 05 16; 177(5):1201-1216.e19.
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Inhibition of IRE1 results in decreased scar formation. Wound Repair Regen. 2017 11; 25(6):964-971.
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Peroxisome Proliferator-activated Receptor-? Activation Augments the ß-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and ß Cell Death in Non-obese Diabetic Mice. J Biol Chem. 2016 Oct 21; 291(43):22524-22533.
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IRS1 deficiency protects ß-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation. Sci Rep. 2016 07 05; 6:28177.
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Intravenous Lipid Infusion Induces Endoplasmic Reticulum Stress in Endothelial Cells and Blood Mononuclear Cells of Healthy Adults. J Am Heart Assoc. 2016 Jan 11; 5(1).
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Divergent allosteric control of the IRE1a endoribonuclease using kinase inhibitors. Nat Chem Biol. 2012 Dec; 8(12):982-9.
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Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis. J Hepatol. 2010 Apr; 52(4):586-93.