"Single Molecule Imaging" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High resolution imaging techniques that allow visualization of individual molecules of proteins, lipids, or nucleic acids within cells or tissues.
Descriptor ID |
D000072760
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MeSH Number(s) |
E01.370.350.515.899 E01.370.350.557.750 E05.595.899 E05.601.555.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Single Molecule Imaging".
Below are MeSH descriptors whose meaning is more specific than "Single Molecule Imaging".
This graph shows the total number of publications written about "Single Molecule Imaging" by people in this website by year, and whether "Single Molecule Imaging" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 1 | 3 | 4 |
2019 | 0 | 1 | 1 |
2020 | 1 | 1 | 2 |
2021 | 1 | 1 | 2 |
2022 | 1 | 1 | 2 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Single Molecule Imaging" by people in Profiles.
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Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function. Nat Commun. 2024 Dec 04; 15(1):10545.
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Minimizing Molecular Misidentification in Imaging Low-Abundance Protein Interactions Using Spectroscopic Single-Molecule Localization Microscopy. Anal Chem. 2022 10 11; 94(40):13834-13841.
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Sub-3-Å cryo-EM structure of RNA enabled by engineered homomeric self-assembly. Nat Methods. 2022 05; 19(5):576-585.
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Molecular design of the ?dT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing. Proc Natl Acad Sci U S A. 2021 06 29; 118(26).
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FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices. Elife. 2021 03 29; 10.
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Mechanical expansion microscopy. Methods Cell Biol. 2021; 161:125-146.
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A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution. Nat Chem Biol. 2020 06; 16(6):660-666.
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Quantitative Mapping of Endosomal DNA Processing by Single Molecule Counting. Angew Chem Int Ed Engl. 2019 03 04; 58(10):3073-3076.
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Dynamics of Membrane-Bound G12V-KRAS from Simulations and Single-Molecule FRET in Native Nanodiscs. Biophys J. 2019 01 22; 116(2):179-183.
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Conducting Multiple Imaging Modes with One Fluorescence Microscope. J Vis Exp. 2018 10 28; (140).