"Frailty" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A state of increased vulnerability to stressors, following declines in function and reserves across multiple physiologic systems, characterized by MUSCLE WEAKNESS; FATIGUE; slowed motor performance; low physical activity; and unintentional weight loss.
| Descriptor ID |
D000073496
|
| MeSH Number(s) |
C23.550.359
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Frailty".
Below are MeSH descriptors whose meaning is more specific than "Frailty".
This graph shows the total number of publications written about "Frailty" by people in this website by year, and whether "Frailty" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2018 | 4 | 1 | 5 |
| 2019 | 3 | 3 | 6 |
| 2020 | 8 | 0 | 8 |
| 2021 | 5 | 0 | 5 |
| 2022 | 7 | 0 | 7 |
| 2023 | 12 | 0 | 12 |
| 2024 | 12 | 4 | 16 |
| 2025 | 5 | 0 | 5 |
| 2026 | 2 | 0 | 2 |
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Below are the most recent publications written about "Frailty" by people in Profiles.
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Circadian feeding promotion by Ninjin'yoeito counteracts frailty in aged mice. J Physiol Sci. 2026 Mar; 76(1):100062.
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Frailty and risk of death without device therapy among patients with primary prophylaxis implantable cardioverter-defibrillators: The CERTITUDE Registry. Heart Rhythm. 2026 06; 23(6):e930-e939.
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Circulating mitokines GDF-15 and FGF21 are associated with frailty, sarcopenia, and malnutrition in older adults: Evidence from the FRASNET study. Mech Ageing Dev. 2025 12; 228:112124.
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Unique Opportunity and Motivational Targets for Exercise Behavior Change Among Nonfrail, Prefrail, and Frail Older Adults. J Aging Phys Act. 2026 04 01; 34(2):221-233.
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Impact of Mild Frailty on Quantitative Measures of Oropharyngeal Swallow. Laryngoscope. 2025 09; 135(9):3112-3119.
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Longitudinal Association of Olfactory Function with Frailty in Older Adults: The Atherosclerosis Risk in Communities Study. J Gerontol A Biol Sci Med Sci. 2025 03 07; 80(4).
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Applying the Modified Five-Item Frailty Index to Predict Complications following Lower Extremity Free Flap Reconstruction in Trauma Patients. J Reconstr Microsurg. 2025 Nov; 41(9):746-751.
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The Association of Modified 5-Item Frailty Index on Perioperative Cochlear Implant Speech Perception. Otol Neurotol. 2025 02 01; 46(2):140-147.
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Association of Frailty Index and Postoperative Outcomes of Open Bypass Lower Extremity Revascularization for Acute Limb Ischemia Using the Vascular Quality Initiative. Vasc Endovascular Surg. 2025 May; 59(4):387-395.
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Comparison of a Risk Calculator With Frailty Indices in Patients Undergoing Lung Cancer Resection. J Surg Oncol. 2024 Dec; 130(8):1532-1538.