Retinoic Acid Receptor alpha
"Retinoic Acid Receptor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear receptor protein which belongs to a family of transcription regulators of ligand-responsive regulatory proteins which include steroid hormone receptors. In addition to a C-terminal ligand-binding domain, these nuclear receptors contain a highly-conserved N-terminal zinc-finger domain that mediates binding ligand-responsive elements.
| Descriptor ID |
D000072482
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| MeSH Number(s) |
D12.776.826.701.250 D12.776.930.775.250
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinoic Acid Receptor alpha".
Below are MeSH descriptors whose meaning is more specific than "Retinoic Acid Receptor alpha".
This graph shows the total number of publications written about "Retinoic Acid Receptor alpha" by people in this website by year, and whether "Retinoic Acid Receptor alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinoic Acid Receptor alpha" by people in Profiles.
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Mechanism underlying the suppressor activity of retinoic acid on IL4-induced IgE synthesis and its physiological implication. Cell Immunol. 2017 Dec; 322:49-55.
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FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase. Cancer Cell. 2017 01 09; 31(1):127-141.
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Retinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program. Immunity. 2015 Mar 17; 42(3):499-511.
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All-trans retinoic acid inhibits tumor growth of human osteosarcoma by activating Smad signaling-induced osteogenic differentiation. Int J Oncol. 2012 Jul; 41(1):153-60.
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Discovering transcription factor regulatory targets using gene expression and binding data. Bioinformatics. 2012 Jan 15; 28(2):206-13.
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Retinoic acids potentiate BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. PLoS One. 2010 Jul 30; 5(7):e11917.
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Synergistic antitumor effect of the activated PPARgamma and retinoid receptors on human osteosarcoma. Clin Cancer Res. 2010 Apr 15; 16(8):2235-45.
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Genomic antagonism between retinoic acid and estrogen signaling in breast cancer. Cell. 2009 Jun 26; 137(7):1259-71.
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SMRT recruitment by PPARgamma is mediated by specific residues located in its carboxy-terminal interacting domain. Mol Cell Endocrinol. 2006 Oct 19; 259(1-2):43-9.
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Durable molecular remissions with a single cycle of timed sequential consolidation chemotherapy in acute promyelocytic leukemia. Am J Hematol. 2005 Jun; 79(2):119-27.