Intraepithelial Lymphocytes
"Intraepithelial Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
T Lymphocytes with limited diversity of receptors (e.g., ALPHA E INTEGRINS) in the epidermis of the skin and the mucosal linings. They recognize common microbes via T-CELL RECEPTORS and PATHOGEN-ASSOCIATED MOLECULAR PATTERN MOLECULES and function as effector cells for INNATE IMMUNITY. Activation of intraepithelial lymphocytes is a marker for various gastrointestinal diseases (e.g., CELIAC DISEASE; HAIRY CELL LEUKEMIA; and ENTEROPATHY-ASSOCIATED T-CELL LYMPHOMA).
| Descriptor ID |
D000075942
|
| MeSH Number(s) |
A11.118.637.555.567.550.500.050 A11.118.637.555.567.569.500.050 A15.145.229.637.555.567.550.500.050 A15.145.229.637.555.567.569.500.050 A15.382.490.555.567.550.500.050 A15.382.490.555.567.569.500.050
|
| Concept/Terms |
Intraepithelial Lymphocytes- Intraepithelial Lymphocytes
- Intraepithelial Lymphocyte
- Lymphocyte, Intraepithelial
- Lymphocytes, Intraepithelial
- Gamma Delta T Lymphocytes
- Intraepithelial T Cells
- Intraepithelial T Cell
- T Cell, Intraepithelial
- T Cells, Intraepithelial
- Mucosal T Lymphocytes
- Mucosal T Lymphocyte
- T Lymphocyte, Mucosal
- T Lymphocytes, Mucosal
- Mucosal T Cells
- Mucosal T Cell
- T Cell, Mucosal
- T Cells, Mucosal
- Gamma Delta T Cells
- Intraepithelial T Lymphocytes
- Intraepithelial T Lymphocyte
- T Lymphocyte, Intraepithelial
- T Lymphocytes, Intraepithelial
|
Below are MeSH descriptors whose meaning is more general than "Intraepithelial Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "Intraepithelial Lymphocytes".
This graph shows the total number of publications written about "Intraepithelial Lymphocytes" by people in this website by year, and whether "Intraepithelial Lymphocytes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 2 | 0 | 2 |
| 2018 | 3 | 0 | 3 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Intraepithelial Lymphocytes" by people in Profiles.
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NK-like CD8+ ?d T cells are expanded in persistent Mycobacterium tuberculosis infection. Sci Immunol. 2023 03 31; 8(81):eade3525.
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Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes. J Autoimmun. 2020 03; 108:102422.
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Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease. Cell. 2019 02 21; 176(5):967-981.e19.
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Gut immune cells have a role in food metabolism. Nature. 2019 02; 566(7742):49-50.
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Diverse developmental pathways of intestinal intraepithelial lymphocytes. Nat Rev Immunol. 2018 08; 18(8):514-525.
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Mitochondria maintain controlled activation state of epithelial-resident T lymphocytes. Sci Immunol. 2018 06 22; 3(24).
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Epithelial IL-15 Is a Critical Regulator of ?d Intraepithelial Lymphocyte Motility within the Intestinal Mucosa. J Immunol. 2018 07 15; 201(2):747-756.
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A shared Runx1-bound Zbtb16 enhancer directs innate and innate-like lymphoid lineage development. Nat Commun. 2017 10 16; 8(1):863.
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Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on V?9Vd2 T cell activation. Proc Natl Acad Sci U S A. 2017 08 29; 114(35):E7311-E7320.