Mucosal-Associated Invariant T Cells
"Mucosal-Associated Invariant T Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of T-lymphocytes that are present in large numbers at MUCOUS MEMBRANES and respond to INFECTIONS. They express a conserved invariant T-CELL RECEPTOR ALPHA-CHAIN that enables them to respond to infections by sensing RIBOFLAVIN metabolites of pathogens.
| Descriptor ID |
D000072336
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| MeSH Number(s) |
A11.118.637.555.567.550.500.100 A11.118.637.555.567.569.500.100 A15.145.229.637.555.567.550.500.100 A15.145.229.637.555.567.569.500.100 A15.382.490.555.567.550.500.100 A15.382.490.555.567.569.500.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mucosal-Associated Invariant T Cells".
Below are MeSH descriptors whose meaning is more specific than "Mucosal-Associated Invariant T Cells".
This graph shows the total number of publications written about "Mucosal-Associated Invariant T Cells" by people in this website by year, and whether "Mucosal-Associated Invariant T Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 1 | 3 |
| 2020 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mucosal-Associated Invariant T Cells" by people in Profiles.
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Multiple Isomers of Photolumazine V Bind MR1 and Differentially Activate MAIT Cells. J Immunol. 2024 Mar 15; 212(6):933-940.
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Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells. Sci Rep. 2022 12 29; 12(1):22539.
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The transcription factor BCL-6 controls early development of innate-like T cells. Nat Immunol. 2020 09; 21(9):1058-1069.
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Production of MR1 Tetramers Loaded with Microbial Ligands. Methods Mol Biol. 2020; 2098:191-207.
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MAIT cells are imprinted by the microbiota in early life and promote tissue repair. Science. 2019 10 25; 366(6464).
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Mucosal-activated invariant T cells do not exhibit significant lung recruitment and proliferation profiles in macaques in response to infection with Mycobacterium tuberculosis CDC1551. Tuberculosis (Edinb). 2019 05; 116S:S11-S18.
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Select sequencing of clonally expanded CD8+ T cells reveals limits to clonal expansion. Proc Natl Acad Sci U S A. 2019 04 30; 116(18):8995-9001.
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MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage. Sci Immunol. 2018 07 13; 3(25).
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MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates. Mucosal Immunol. 2017 05; 10(3):802-813.