"Cell Adhesion Molecule-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.
| Descriptor ID |
D000075982
|
| MeSH Number(s) |
D12.776.395.550.200.115 D12.776.543.550.200.128 D23.050.301.350.115
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| Concept/Terms |
Cell Adhesion Molecule-1- Cell Adhesion Molecule-1
- Adhesion Molecule-1, Cell
- Cell Adhesion Molecule 1
- Molecule-1, Cell Adhesion
- CADM1 Protein
- Tumor Suppressor in Lung Cancer 1 Protein
- IGSF4 Protein
- TSLC1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Cell Adhesion Molecule-1".
Below are MeSH descriptors whose meaning is more specific than "Cell Adhesion Molecule-1".
This graph shows the total number of publications written about "Cell Adhesion Molecule-1" by people in this website by year, and whether "Cell Adhesion Molecule-1" was a major or minor topic of these publications.
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Below are the most recent publications written about "Cell Adhesion Molecule-1" by people in Profiles.
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Necl-4/SynCAM-4 is expressed in myelinating oligodendrocytes but not required for axonal myelination. PLoS One. 2013; 8(5):e64264.
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The synaptic adhesion molecule SynCAM 1 contributes to cocaine effects on synapse structure and psychostimulant behavior. Neuropsychopharmacology. 2013 Mar; 38(4):628-38.