"Nectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of calcium-independent cell adhesion molecules of the immunoglobulin superfamily. They are expressed by most cell types and mediate both homotypic and heterotypic cell-cell adhesion. Nectins function in a variety of morphogenetic and developmental processes that include organogenesis of the eye, ear, tooth, and cerebral cortex; they also play roles in viral infection and cell proliferation.
| Descriptor ID |
D000075983
|
| MeSH Number(s) |
D12.776.395.550.200.123 D12.776.543.550.200.130 D23.050.301.350.123
|
| Concept/Terms |
Nectin-2- Nectin-2
- Nectin 2
- CD112 Antigen
- Antigen, CD112
Nectin-3- Nectin-3
- Nectin 3
- CD113 Antigen
- Antigen, CD113
Nectin-1- Nectin-1
- Nectin 1
- Herpesvirus Entry Mediator C
- Human Poliovirus Receptor Related 1
- PVRL1
- CD111 Antigen
- Antigen, CD111
- HevC Protein
- Poliovirus Receptor-Related Protein 1
- Poliovirus Receptor Related Protein 1
- Prr1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Nectins".
Below are MeSH descriptors whose meaning is more specific than "Nectins".
This graph shows the total number of publications written about "Nectins" by people in this website by year, and whether "Nectins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Nectins" by people in Profiles.
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In Reply. Oncologist. 2022 10 01; 27(10):e827-e828.
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Management of Dermatologic Events Associated With the Nectin-4-directed Antibody-Drug Conjugate Enfortumab Vedotin. Oncologist. 2022 03 11; 27(3):e223-e232.
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Assessment of oncolytic HSV efficacy following increased entry-receptor expression in malignant peripheral nerve sheath tumor cell lines. Gene Ther. 2014 Nov; 21(11):984-90.
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HSV-1 infection of human corneal epithelial cells: receptor-mediated entry and trends of re-infection. Mol Vis. 2010 Nov 20; 16:2476-86.
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Mediators and mechanisms of herpes simplex virus entry into ocular cells. Curr Eye Res. 2010 Jun; 35(6):445-50.
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Expression of nectin-1 in normal and herpes simplex virus type 1-infected murine brain. Appl Immunohistochem Mol Morphol. 2006 Sep; 14(3):341-7.
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Herpes simplex virus entry receptor nectin-1 is widely expressed in the murine eye. Curr Eye Res. 2004 Oct-Nov; 29(4-5):303-9.
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The domains of glycoprotein D required to block apoptosis induced by herpes simplex virus 1 are largely distinct from those involved in cell-cell fusion and binding to nectin1. J Virol. 2003 Mar; 77(6):3759-67.