"Hyaluronan Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.
Descriptor ID |
D000076002
|
MeSH Number(s) |
D08.811.913.400.450.480.500
|
Concept/Terms |
Hyaluronan Synthases- Hyaluronan Synthases
- Synthases, Hyaluronan
- Hyaluronan Synthase
- Synthase, Hyaluronan
- Hyaluronic Acid Synthetase
- Synthetase, Hyaluronic Acid
- Hyaluronate Synthetase
- Synthetase, Hyaluronate
- Hyaluronan Synthetase
- Synthetase, Hyaluronan
- Hyaluronate Synthase
- Synthase, Hyaluronate
Hyaluronan Synthase 3- Hyaluronan Synthase 3
- 3, Hyaluronan Synthase
- Synthase 3, Hyaluronan
- HAS3 Protein
- Protein, HAS3
|
Below are MeSH descriptors whose meaning is more general than "Hyaluronan Synthases".
Below are MeSH descriptors whose meaning is more specific than "Hyaluronan Synthases".
This graph shows the total number of publications written about "Hyaluronan Synthases" by people in this website by year, and whether "Hyaluronan Synthases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2012 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Hyaluronan Synthases" by people in Profiles.
-
Rapid evolution of hyaluronan synthase to improve hyaluronan production and molecular mass in Bacillus subtilis. Biotechnol Lett. 2016 Dec; 38(12):2103-2108.
-
The hyaluronic acid inhibitor 4-methylumbelliferone is an NSMase2 activator-role of Ceramide in MU anti-tumor activity. Biochim Biophys Acta. 2016 Feb; 1861(2):78-90.
-
Neutral sphingomyelinase 2 deficiency increases hyaluronan synthesis by up-regulation of Hyaluronan synthase 2 through decreased ceramide production and activation of Akt. J Biol Chem. 2012 Apr 20; 287(17):13620-32.
-
Role of hyaluronan and hyaluronan-binding proteins in lung pathobiology. Am J Physiol Lung Cell Mol Physiol. 2011 Aug; 301(2):L137-47.
-
Solubilization and partial purification of hyaluronate synthetase from oligodendroglioma cells. J Biol Chem. 1989 Jul 15; 264(20):11776-83.
-
Effect of hyaluronidase treatment of intact cells on hyaluronate synthetase activity. Biochemistry. 1985 Dec 31; 24(27):7899-906.
-
Subcellular localization of hyaluronate synthetase in oligodendroglioma cells. J Biol Chem. 1984 Apr 25; 259(8):5017-23.
-
Regulation of glycosaminoglycan synthesis by thyroid hormone in vitro. J Clin Invest. 1982 Nov; 70(5):1066-73.