alpha7 Nicotinic Acetylcholine Receptor
"alpha7 Nicotinic Acetylcholine Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the NICOTINIC ACETYLCHOLINE RECEPTOR subfamily of the LIGAND-GATED ION CHANNEL family. It consists entirely of pentameric α7 subunits expressed in the CNS, autonomic nervous system, vascular system, lymphocytes and spleen.
| Descriptor ID |
D064569
|
| MeSH Number(s) |
D12.776.157.530.400.400.100.500.500 D12.776.543.550.450.500.100.500.500 D12.776.543.585.400.500.100.500.500 D12.776.543.750.130.687.500 D12.776.543.750.720.360.550.500
|
| Concept/Terms |
Receptor, alpha-Bungarotoxin- Receptor, alpha-Bungarotoxin
- Receptor, alpha Bungarotoxin
- alpha-Bungarotoxin Receptor
- alpha-Bungarotoxin Receptors
- Receptors, alpha-Bungarotoxin
- alpha Bungarotoxin Receptors
|
Below are MeSH descriptors whose meaning is more general than "alpha7 Nicotinic Acetylcholine Receptor".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, Nicotinic [D12.776.157.530.400.400.100.500]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.157.530.400.400.100.500.500]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, Nicotinic [D12.776.543.550.450.500.100.500]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.550.450.500.100.500.500]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, Nicotinic [D12.776.543.585.400.500.100.500]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.585.400.500.100.500.500]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, Nicotinic [D12.776.543.750.130.687]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.750.130.687.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Nicotinic [D12.776.543.750.720.360.550]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.750.720.360.550.500]
Below are MeSH descriptors whose meaning is more specific than "alpha7 Nicotinic Acetylcholine Receptor".
This graph shows the total number of publications written about "alpha7 Nicotinic Acetylcholine Receptor" by people in this website by year, and whether "alpha7 Nicotinic Acetylcholine Receptor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "alpha7 Nicotinic Acetylcholine Receptor" by people in Profiles.
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Prefrontal a7nAChR Signaling Differentially Modulates Afferent Drive and Trace Fear Conditioning Behavior in Adolescent and Adult Rats. J Neurosci. 2021 03 03; 41(9):1908-1916.
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Thermodynamics and Kinetics of Ion Permeation in Wild-Type and Mutated Open Active Conformation of the Human a7 Nicotinic Receptor. J Chem Inf Model. 2020 10 26; 60(10):5045-5056.
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Closed-Locked and Apo-Resting State Structures of the Human a7 Nicotinic Receptor: A Computational Study. J Chem Inf Model. 2018 11 26; 58(11):2278-2293.
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a7 nicotinic acetylcholine receptor signaling modulates the inflammatory phenotype of fetal brain microglia: first evidence of interference by iron homeostasis. Sci Rep. 2017 09 06; 7(1):10645.
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A possible desensitized state conformation of the human a7 nicotinic receptor: A molecular dynamics study. Biophys Chem. 2017 10; 229:99-109.
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Ethanol-Induced Motor Impairment Mediated by Inhibition of a7 Nicotinic Receptors. J Neurosci. 2016 07 20; 36(29):7768-78.
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Nicotinic receptors and lurasidone-mediated reversal of phencyclidine-induced deficit in novel object recognition. Behav Brain Res. 2016 Mar 15; 301:204-12.
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A Structural Model of the Human a7 Nicotinic Receptor in an Open Conformation. PLoS One. 2015; 10(7):e0133011.
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Counting bungarotoxin binding sites of nicotinic acetylcholine receptors in mammalian cells with high signal/noise ratios. Biophys J. 2010 Nov 17; 99(10):L81-3.
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Ric-3 promotes alpha7 nicotinic receptor assembly and trafficking through the ER subcompartment of dendrites. J Neurosci. 2010 Jul 28; 30(30):10112-26.