"Claudin-5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.
| Descriptor ID |
D062507
|
| MeSH Number(s) |
D12.776.543.940.200.500
|
| Concept/Terms |
Claudin-5- Claudin-5
- Transmembrane Protein Deleted in Velocardiofacial Syndrome
- TMVCF Protein
- Claudin 5
|
Below are MeSH descriptors whose meaning is more general than "Claudin-5".
Below are MeSH descriptors whose meaning is more specific than "Claudin-5".
This graph shows the total number of publications written about "Claudin-5" by people in this website by year, and whether "Claudin-5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Claudin-5" by people in Profiles.
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Increased Type I interferon signaling and brain endothelial barrier dysfunction in an experimental model of Alzheimer's disease. Sci Rep. 2022 10 01; 12(1):16488.
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Computational Assessment of Different Structural Models for Claudin-5 Complexes in Blood-Brain Barrier Tight Junctions. ACS Chem Neurosci. 2022 07 20; 13(14):2140-2153.
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Claudin-1-Dependent Destabilization of the Blood-Brain Barrier in Chronic Stroke. J Neurosci. 2019 01 23; 39(4):743-757.
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C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus. Immunology. 2015 Sep; 146(1):130-43.