"Phosphofructokinase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.
| Descriptor ID |
D010732
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| MeSH Number(s) |
D08.811.913.696.620.225.850.500
|
| Concept/Terms |
Phosphofructokinase-1- Phosphofructokinase-1
- Phosphofructokinase 1
- 6-Phosphofructokinase
- 6 Phosphofructokinase
- Fructose-6-phosphate 1-Phosphotransferase
- 6-Phosphofructo-1-kinase
- Fructose-6-P 1-Kinase
|
Below are MeSH descriptors whose meaning is more general than "Phosphofructokinase-1".
Below are MeSH descriptors whose meaning is more specific than "Phosphofructokinase-1".
This graph shows the total number of publications written about "Phosphofructokinase-1" by people in this website by year, and whether "Phosphofructokinase-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphofructokinase-1" by people in Profiles.
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Phosphorylation of Bad at Thr-201 by JNK1 promotes glycolysis through activation of phosphofructokinase-1. J Biol Chem. 2008 Jul 25; 283(30):20754-60.
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Mode of interaction of phosphofructokinase with the erythrocyte membrane. J Biol Chem. 1985 Sep 05; 260(19):10426-33.
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Association of phosphofructokinase and aldolase with the membrane of the intact erythrocyte. J Biol Chem. 1984 Aug 10; 259(15):9374-8.
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Physiology of a temperature-sensitive mutant of Saccharomyces cerevisiae defective in phosphofructokinase activity. J Bacteriol. 1984 Apr; 158(1):94-101.
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Transformation of energy charge and phosphofructokinase activity in alveolar macrophages. J Reticuloendothel Soc. 1981 May; 29(5):407-12.