Polymorphism, Single-Stranded Conformational
"Polymorphism, Single-Stranded Conformational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
| Descriptor ID |
D018807
|
| MeSH Number(s) |
G05.365.795.600
|
| Concept/Terms |
Polymorphism, Single-Stranded Conformational- Polymorphism, Single-Stranded Conformational
- Polymorphism, Single Stranded Conformational
- SSCP
- Single-Stranded Conformational Polymorphism
- Conformational Polymorphism, Single-Stranded
- Conformational Polymorphisms, Single-Stranded
- Polymorphisms, Single-Stranded Conformational
- Single Stranded Conformational Polymorphism
- Single-Stranded Conformational Polymorphisms
|
Below are MeSH descriptors whose meaning is more general than "Polymorphism, Single-Stranded Conformational".
Below are MeSH descriptors whose meaning is more specific than "Polymorphism, Single-Stranded Conformational".
This graph shows the total number of publications written about "Polymorphism, Single-Stranded Conformational" by people in this website by year, and whether "Polymorphism, Single-Stranded Conformational" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 2 | 3 |
| 1996 | 0 | 5 | 5 |
| 1997 | 2 | 6 | 8 |
| 1999 | 1 | 2 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polymorphism, Single-Stranded Conformational" by people in Profiles.
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The SPINK1 N34S variant is associated with acute pancreatitis. Eur J Gastroenterol Hepatol. 2008 Aug; 20(8):726-31.
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Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood. 2007 Jul 15; 110(2):719-26.
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KAL1 mutations are not a common cause of idiopathic hypogonadotrophic hypogonadism in humans. Mol Hum Reprod. 2007 Mar; 13(3):165-70.
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Differential recruitment of caspase 8 to cFlip confers sensitivity or resistance to Fas-mediated apoptosis in a subset of familial lymphoma patients. Leuk Res. 2003 Sep; 27(9):841-51.
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Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet. 2002 Sep; 32(1):148-52.
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Linkage of Patr-AL to Patr-A and- B in the major histocompatibility complex of the common chimpanzee (Pan troglodytes). Immunogenetics. 2002 Jun; 54(3):212-5.
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Tandem pore domain K(+)-channel TASK-3 (KCNK9) and idiopathic absence epilepsies. Am J Med Genet. 2002 Mar 08; 114(2):227-9.
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Mutations in the X-linked filamin 1 gene cause periventricular nodular heterotopia in males as well as in females. Hum Mol Genet. 2001 Aug 15; 10(17):1775-83.
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Genomic organization of the SLC1A1/EAAC1 gene and mutation screening in early-onset obsessive-compulsive disorder. Mol Psychiatry. 2001 Mar; 6(2):160-7.
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cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins. Genomics. 2000 Nov 15; 70(1):123-30.