"2,3-Diphosphoglycerate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
| Descriptor ID |
D019794
|
| MeSH Number(s) |
D02.241.081.844.387.388.175 D02.241.511.902.387.388.175 D02.705.400.140.175 D09.811.366.388.175
|
| Concept/Terms |
2,3-Diphosphoglycerate- 2,3-Diphosphoglycerate
- 2,3 Diphosphoglycerate
- 2,3-DPG
- Glycerate 2,3-Bisphosphate
- 2,3-Bisphosphate, Glycerate
- 2,3-Bisphosphoglycerate
- 2,3 Bisphosphoglycerate
|
Below are MeSH descriptors whose meaning is more general than "2,3-Diphosphoglycerate".
Below are MeSH descriptors whose meaning is more specific than "2,3-Diphosphoglycerate".
This graph shows the total number of publications written about "2,3-Diphosphoglycerate" by people in this website by year, and whether "2,3-Diphosphoglycerate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "2,3-Diphosphoglycerate" by people in Profiles.
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Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nat Commun. 2013; 4:1790.
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Mechanisms of hemolysate-induced [Ca2+]i elevation in cerebral smooth muscle cells. Am J Physiol. 1995 Dec; 269(6 Pt 2):H1874-90.
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31P MRS of myocardial inorganic phosphate using radiofrequency gradient echoes. Magn Reson Med. 1991 Aug; 20(2):171-83.