"Receptor, Muscarinic M1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific subtype of muscarinic receptor that has a high affinity for the drug PIRENZEPINE. It is found in the peripheral GANGLIA where it signals a variety of physiological functions such as GASTRIC ACID secretion and BRONCHOCONSTRICTION. This subtype of muscarinic receptor is also found in neuronal tissues including the CEREBRAL CORTEX and HIPPOCAMPUS where it mediates the process of MEMORY and LEARNING.
| Descriptor ID |
D043643
|
| MeSH Number(s) |
D12.776.543.750.695.475.100 D12.776.543.750.720.360.500.099
|
| Concept/Terms |
Receptor, Muscarinic M1- Receptor, Muscarinic M1
- M1 Receptor, Muscarinic
- Muscarinic M1 Receptor
- Receptors, Muscarinic M1
- M1 Receptors, Muscarinic
- Muscarinic M1 Receptors
- Muscarinic Receptor M1
- M1, Muscarinic Receptor
- Receptor M1, Muscarinic
- Muscarinic Receptors M1
- M1, Muscarinic Receptors
- Receptors M1, Muscarinic
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Muscarinic M1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Muscarinic [D12.776.543.750.695.475]
- Receptor, Muscarinic M1 [D12.776.543.750.695.475.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Muscarinic [D12.776.543.750.720.360.500]
- Receptor, Muscarinic M1 [D12.776.543.750.720.360.500.099]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Muscarinic M1".
This graph shows the total number of publications written about "Receptor, Muscarinic M1" by people in this website by year, and whether "Receptor, Muscarinic M1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Muscarinic M1" by people in Profiles.
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Muscarinic receptor signaling contributes to atypical antipsychotic drug reversal of the phencyclidine-induced deficit in novel object recognition in rats. J Psychopharmacol. 2017 12; 31(12):1588-1604.
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Dynamic Regulation of Quaternary Organization of the M1 Muscarinic Receptor by Subtype-selective Antagonist Drugs. J Biol Chem. 2016 Jun 17; 291(25):13132-46.
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Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor. Nature. 2006 Nov 02; 444(7115):106-9.
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Dopaminergic control of corticostriatal long-term synaptic depression in medium spiny neurons is mediated by cholinergic interneurons. Neuron. 2006 May 04; 50(3):443-52.