"Receptor, Muscarinic M2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific subtype of muscarinic receptor found in the lower BRAIN, the HEART and in SMOOTH MUSCLE-containing organs. Although present in smooth muscle the M2 muscarinic receptor appears not to be involved in contractile responses.
| Descriptor ID |
D043585
|
| MeSH Number(s) |
D12.776.543.750.695.475.200 D12.776.543.750.720.360.500.200
|
| Concept/Terms |
Receptor, Muscarinic M2- Receptor, Muscarinic M2
- M2 Receptor, Muscarinic
- Muscarinic M2 Receptor
- Receptors, Muscarinic M2
- M2 Receptors, Muscarinic
- Muscarinic M2 Receptors
- Muscarinic Receptor M2
- M2, Muscarinic Receptor
- Receptor M2, Muscarinic
- Muscarinic Receptors M2
- M2, Muscarinic Receptors
- Receptors M2, Muscarinic
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Muscarinic M2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Muscarinic [D12.776.543.750.695.475]
- Receptor, Muscarinic M2 [D12.776.543.750.695.475.200]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Muscarinic [D12.776.543.750.720.360.500]
- Receptor, Muscarinic M2 [D12.776.543.750.720.360.500.200]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Muscarinic M2".
This graph shows the total number of publications written about "Receptor, Muscarinic M2" by people in this website by year, and whether "Receptor, Muscarinic M2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptor, Muscarinic M2" by people in Profiles.
-
Identification and characterization of fragment binding sites for allosteric ligand design using the site identification by ligand competitive saturation hotspots approach (SILCS-Hotspots). Biochim Biophys Acta Gen Subj. 2020 04; 1864(4):129519.
-
A Novel Voltage Sensor in the Orthosteric Binding Site of the M2 Muscarinic Receptor. Biophys J. 2016 Oct 04; 111(7):1396-1408.
-
Depolarization induces a conformational change in the binding site region of the M2 muscarinic receptor. Proc Natl Acad Sci U S A. 2012 Jan 03; 109(1):285-90.
-
Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation. Cardiovasc Res. 2009 Aug 01; 83(3):481-92.
-
Neural substrate for atrial fibrillation: implications for targeted parasympathetic blockade in the posterior left atrium. Am J Physiol Heart Circ Physiol. 2008 Jan; 294(1):H134-44.
-
Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor. Nature. 2006 Nov 02; 444(7115):106-9.
-
Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or nicotine in rats. Arch Toxicol. 2003 Aug; 77(8):452-8.
-
Uranyl acetate-induced sensorimotor deficit and increased nitric oxide generation in the central nervous system in rats. Pharmacol Biochem Behav. 2002 Jul; 72(4):881-90.
-
Sensorimotor deficit and cholinergic changes following coexposure with pyridostigmine bromide and sarin in rats. Toxicol Sci. 2002 Mar; 66(1):148-58.
-
Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination. Toxicol Sci. 2001 Apr; 60(2):305-14.