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Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions.
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Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions.
Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions. PLoS One. 2015; 10(2):e0118307.
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PubMed
subject areas
Cell Culture Techniques
Cell Differentiation
Cell Line
Cell Self Renewal
Cell Transformation, Neoplastic
Cells, Cultured
Chromosome Aberrations
Chromosome Deletion
Chromosome Duplication
Chromosomes, Human, Pair 12
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 20
DNA Methylation
Epigenesis, Genetic
Gene Expression Profiling
Genome, Human
Genomic Instability
Human Embryonic Stem Cells
Humans
Phenotype
Pluripotent Stem Cells
Polymorphism, Single Nucleotide
Time Factors
Tumor Suppressor Protein p53