PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia.

PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia. Brain. 2015 Jun; 138(Pt 6):1613-28.

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subject areas

Adolescent
Brain
Child
Child, Preschool
Class I Phosphatidylinositol 3-Kinases
Female
Genetic Predisposition to Disease
Hemimegalencephaly
Humans
Infant
Infant, Newborn
Magnetic Resonance Imaging
Male
Malformations of Cortical Development
Megalencephaly
Mutation
Neuroimaging
Phosphatidylinositol 3-Kinases
Proto-Oncogene Proteins c-akt
PTEN Phosphohydrolase
Ribosomal Protein S6 Kinases
Signal Transduction

authors with profiles

William B. Dobyns