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Chen, Jing
One or more keywords matched the following properties of
Chen, Jing
Property
Value
keywords
Leukemia
keywords
Drug discovery and development
One or more keywords matched the following items that are connected to
Chen, Jing
Item Type
Name
Concept
Models, Molecular
Concept
Mice, Transgenic
Concept
Mice, Nude
Concept
Humans
Concept
Leukemia, Myeloid, Acute
Concept
Mice
Concept
Leukemia, Hairy Cell
Concept
Models, Biological
Concept
Mice, Inbred NOD
Academic Article
Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.
Academic Article
Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth.
Academic Article
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation.
Academic Article
Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex.
Academic Article
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Academic Article
Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.
Academic Article
Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.
Academic Article
p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells.
Academic Article
Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling.
Academic Article
Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Award or Honor Receipt
LLS Career Development Program Fellow Award
Award or Honor Receipt
LLS Career Development Program Scholar Award
Academic Article
Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer.
Academic Article
The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells.
Academic Article
Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth.
Academic Article
FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway.
Academic Article
?-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A.
Academic Article
Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism.
Academic Article
Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells.
Grant
Metabolic rewiring by oncogenic BRAF V600E links ketogenesis pathway to BRAF-MEK1 signaling
Grant
Oxidative pentose phosphate pathway regulates AMPK homeostasis by balancing opposing LKB1 and PP2A
Academic Article
Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity.
Search Criteria
Development
mouse
models
human
leukemias