| Item Type | Name |
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Concept
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DNA-Binding Proteins
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Concept
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Monosaccharide Transport Proteins
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Concept
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Protein Binding
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Concept
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rho GTP-Binding Proteins
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Concept
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rac1 GTP-Binding Protein
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Concept
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RNA-Binding Protein EWS
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Concept
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RNA-Binding Proteins
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Concept
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rab GTP-Binding Proteins
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Concept
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TATA-Binding Protein Associated Factors
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Concept
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rhoA GTP-Binding Protein
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Concept
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CCAAT-Enhancer-Binding Proteins
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Concept
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Organic Cation Transport Proteins
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Concept
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Fatty Acid-Binding Proteins
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Concept
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Sterol Regulatory Element Binding Protein 1
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Concept
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Insulin-Like Growth Factor Binding Protein 2
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Concept
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GTP-Binding Proteins
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Concept
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cdc42 GTP-Binding Protein
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Concept
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Cation Transport Proteins
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Concept
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RNA-Binding Protein FUS
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Concept
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Calcium-Binding Proteins
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Concept
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Carrier Proteins
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Concept
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Membrane Transport Proteins
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Concept
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Mitochondrial Membrane Transport Proteins
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Concept
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GTP-Binding Protein alpha Subunits, G12-G13
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Academic Article
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The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
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Academic Article
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Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms.
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Academic Article
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Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
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Academic Article
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Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
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Academic Article
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Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
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Academic Article
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Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
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Academic Article
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Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia.
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Academic Article
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Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
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Academic Article
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Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
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Academic Article
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Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
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Academic Article
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The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
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Academic Article
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Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.
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Academic Article
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Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
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Academic Article
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Genome-wide association meta-analysis identifies new endometriosis risk loci.
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Academic Article
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Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.
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Academic Article
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Optineurin mutations in Japanese amyotrophic lateral sclerosis.
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Academic Article
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A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
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Academic Article
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Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer.
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Academic Article
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Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese.
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Academic Article
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Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
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Academic Article
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SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis.
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Academic Article
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IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
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Academic Article
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Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
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Academic Article
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Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
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Academic Article
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Polymorphic human insulin-responsive glucose-transporter gene on chromosome 17p13.
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Academic Article
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A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
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Academic Article
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Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
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Academic Article
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Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
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Academic Article
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Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
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Academic Article
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An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
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Academic Article
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Common variants in CASP3 confer susceptibility to Kawasaki disease.
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Academic Article
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Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.
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Academic Article
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Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
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Academic Article
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Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
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Academic Article
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C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
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Academic Article
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Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
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Academic Article
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Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
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Academic Article
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Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
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Academic Article
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Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
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Academic Article
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TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
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Academic Article
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Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese.
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Academic Article
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Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
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Academic Article
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Cyclin K as a direct transcriptional target of the p53 tumor suppressor.
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Academic Article
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Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.
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Academic Article
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Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
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Academic Article
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Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.
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Academic Article
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Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.
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Academic Article
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An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis.
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Academic Article
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Catalog of 238 variations among six human genes encoding solute carriers ( hSLCs) in the Japanese population.
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Academic Article
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ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
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Academic Article
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Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
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Academic Article
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A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.
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Academic Article
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Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors.
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Academic Article
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Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.
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Academic Article
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Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells.
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Academic Article
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Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
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Academic Article
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Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor.
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Academic Article
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Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis.
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Academic Article
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Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
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Academic Article
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Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
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Academic Article
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Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.
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Academic Article
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Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
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Academic Article
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SNPs in BRAP associated with risk of myocardial infarction in Asian populations.
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Academic Article
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Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
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Academic Article
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Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
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Academic Article
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PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
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Academic Article
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A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
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Academic Article
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Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
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Academic Article
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WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
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Academic Article
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EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK.
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Academic Article
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Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.
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Academic Article
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Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
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Academic Article
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Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
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Academic Article
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High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis.
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Academic Article
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Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
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Academic Article
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Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.
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Academic Article
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Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
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Academic Article
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MRG-binding protein contributes to colorectal cancer development.
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Academic Article
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Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
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Academic Article
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Identification of an HLA-A2-restricted epitope peptide derived from hypoxia-inducible protein 2 (HIG2).
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Academic Article
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Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.
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Academic Article
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Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
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Academic Article
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Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
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Academic Article
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Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
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Academic Article
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ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway.
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Academic Article
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Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
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Academic Article
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Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
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Academic Article
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A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
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Academic Article
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Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
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Academic Article
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Detection of novel cancer-testis antigen-specific T-cell responses in TIL, regional lymph nodes, and PBL in patients with esophageal squamous cell carcinoma.
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Academic Article
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A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability.
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Academic Article
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Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.
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Academic Article
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Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.
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Academic Article
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The p53 family member genes are involved in the Notch signal pathway.
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Academic Article
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SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation.
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Academic Article
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The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
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Academic Article
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Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.
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Academic Article
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Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
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Academic Article
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Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
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Academic Article
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Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
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Academic Article
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Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
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Academic Article
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Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.
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Academic Article
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Identification of COX17 as a therapeutic target for non-small cell lung cancer.
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Academic Article
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Regulation of iron homeostasis by the p53-ISCU pathway.
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Academic Article
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Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases.
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Academic Article
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Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells.
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Academic Article
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Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
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Academic Article
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Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation.
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Academic Article
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Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins.
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Academic Article
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Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors.
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Academic Article
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HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres.
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Academic Article
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WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
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Academic Article
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GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
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Academic Article
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Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
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Academic Article
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A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
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Academic Article
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Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility.
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Academic Article
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SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.
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