| Item Type | Name |
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
MAP Kinase Signaling System
|
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
|
Concept
|
Nod2 Signaling Adaptor Protein
|
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
|
Concept
|
Suppressor of Cytokine Signaling Proteins
|
|
Concept
|
Wnt Signaling Pathway
|
|
Concept
|
Signal Transduction
|
|
Academic Article
|
Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.
|
|
Academic Article
|
Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
|
|
Academic Article
|
Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression.
|
|
Academic Article
|
The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
|
|
Academic Article
|
Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.
|
|
Academic Article
|
Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production.
|
|
Academic Article
|
Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
|
|
Academic Article
|
Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.
|
|
Academic Article
|
Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
|
|
Academic Article
|
PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.
|
|
Academic Article
|
Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.
|
|
Academic Article
|
Functional variants in NFKBIE and RTKN2 involved in activation of the NF-?B pathway are associated with rheumatoid arthritis in Japanese.
|
|
Academic Article
|
A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
|
|
Academic Article
|
Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.
|
|
Academic Article
|
Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
|
|
Academic Article
|
PKIB expression strongly correlated with phosphorylated Akt expression in breast cancers and also with triple-negative breast cancer subtype.
|
|
Academic Article
|
INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.
|
|
Academic Article
|
Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer.
|
|
Academic Article
|
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
|
|
Academic Article
|
Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.
|
|
Academic Article
|
Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.
|
|
Academic Article
|
Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
|
|
Academic Article
|
Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
|
|
Academic Article
|
Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.
|
|
Academic Article
|
p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.
|
|
Academic Article
|
Crosstalk of EDA-A2/XEDAR in the p53 signaling pathway.
|
|
Academic Article
|
DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway.
|
|
Academic Article
|
Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
|
|
Academic Article
|
The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer.
|
|
Academic Article
|
Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy.
|
|
Academic Article
|
Oncogenic role of NALP7 in testicular seminomas.
|
|
Academic Article
|
p53RDL1 regulates p53-dependent apoptosis.
|
|
Academic Article
|
RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.
|
|
Academic Article
|
Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
|
|
Academic Article
|
Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.
|
|
Academic Article
|
A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.
|
|
Academic Article
|
Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas.
|
|
Academic Article
|
Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
|
|
Academic Article
|
Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
|
|
Academic Article
|
Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers.
|
|
Academic Article
|
Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
|
|
Academic Article
|
A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
|
|
Academic Article
|
A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.
|
|
Academic Article
|
Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma.
|
|
Academic Article
|
Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.
|
|
Academic Article
|
Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
|
|
Academic Article
|
Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
|
|
Academic Article
|
Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit.
|
|
Academic Article
|
Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
|
|
Academic Article
|
Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
|
|
Academic Article
|
ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway.
|
|
Academic Article
|
Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
|
|
Academic Article
|
A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.
|
|
Academic Article
|
A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
|
|
Academic Article
|
A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability.
|
|
Academic Article
|
Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
|
|
Academic Article
|
The p53 family member genes are involved in the Notch signal pathway.
|
|
Academic Article
|
Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
|
|
Academic Article
|
The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
|
|
Academic Article
|
Heterozygous TGFBR2 mutations in Marfan syndrome.
|
|
Academic Article
|
An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway.
|
|
Academic Article
|
FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.
|
|
Academic Article
|
Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.
|
|
Academic Article
|
DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
|
|
Academic Article
|
Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.
|
|
Academic Article
|
The NSD family of protein methyltransferases in human cancer.
|
|
Academic Article
|
PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents.
|
|
Academic Article
|
Regulation of iron homeostasis by the p53-ISCU pathway.
|
|
Academic Article
|
SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.
|
|
Academic Article
|
Understanding the functional significance of ghrelin processing and degradation.
|
|
Academic Article
|
Isolation of p53-target genes and their functional analysis.
|
|
Academic Article
|
Retraction: Epstein-Barr virus-encoded latent membrane protein 1 activates ß-catenin signaling in B lymphocytes.
|
|
Academic Article
|
Retraction: Curcumin targets Akt cell survival signaling pathway in HTLV-I-infected T-cell lines.
|
|
Academic Article
|
Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown.
|
|
Academic Article
|
Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
|
|
Academic Article
|
Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
|
|
Academic Article
|
Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
|
|
Academic Article
|
SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1.
|
|
Academic Article
|
Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells.
|
|
Academic Article
|
The Transcriptional Landscape of p53 Signalling Pathway.
|
|
Academic Article
|
Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.
|
|
Academic Article
|
Critical roles of SMYD2-mediated ß-catenin methylation for nuclear translocation and activation of Wnt signaling.
|
|
Concept
|
Suppressor of Cytokine Signaling 1 Protein
|
|
Concept
|
Signaling Lymphocytic Activation Molecule Family
|