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Nakamura, Yusuke
One or more keywords matched the following items that are connected to Nakamura, Yusuke
Item TypeName
Concept Mice, Inbred C3H
Concept Models, Chemical
Concept Models, Molecular
Concept Mice, Transgenic
Concept Models, Genetic
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Mice, Nude
Concept Linear Models
Concept Proportional Hazards Models
Concept Models, Animal
Concept Mice, Knockout
Concept Mice, Inbred MRL lpr
Concept Mice
Concept Models, Statistical
Concept Logistic Models
Concept Hematologic Neoplasms
Concept Disease Models, Animal
Concept Models, Biological
Concept Mice, SCID
Concept Mice, Inbred NOD
Academic Article Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs.
Academic Article Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
Academic Article Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice.
Academic Article Mouse homologue of a novel human oncofetal antigen, glypican-3, evokes T-cell-mediated tumor rejection without autoimmune reactions in mice.
Academic Article Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.
Academic Article Multiplex PCR-based real-time invader assay (mPCR-RETINA): a novel SNP-based method for detecting allelic asymmetries within copy number variation regions.
Academic Article Genome-wide detection and characterization of positive selection in human populations.
Academic Article Genetically manipulated human embryonic stem cell-derived dendritic cells with immune regulatory function.
Academic Article Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
Academic Article Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
Academic Article Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
Academic Article Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression.
Academic Article Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma.
Academic Article Genome-wide association study of intracranial aneurysm identifies three new risk loci.
Academic Article Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.
Academic Article Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
Academic Article Common variation in GPC5 is associated with acquired nephrotic syndrome.
Academic Article Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production.
Academic Article ADAM8 as a novel serological and histochemical marker for lung cancer.
Academic Article Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
Academic Article Evaluating genetic risk for prostate cancer among Japanese and Latinos.
Academic Article Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Academic Article Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response.
Academic Article A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
Academic Article PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.
Academic Article Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.
Academic Article Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen.
Academic Article Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level.
Academic Article Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
Academic Article Nucleotide pyrophosphatase gene polymorphism associated with ossification of the posterior longitudinal ligament of the spine.
Academic Article Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
Academic Article Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction.
Academic Article Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
Academic Article A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
Academic Article Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer.
Academic Article Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
Academic Article An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
Academic Article The textile plot: a new linkage disequilibrium display of multiple-single nucleotide polymorphism genotype data.
Academic Article Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.
Academic Article Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
Academic Article Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Academic Article Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
Academic Article Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.
Academic Article Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin.
Academic Article Histidine augments the suppression of hepatic glucose production by central insulin action.
Academic Article Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
Academic Article Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice.
Academic Article Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
Academic Article Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.
Academic Article Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
Academic Article Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.
Academic Article Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
Academic Article Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
Academic Article Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6).
Academic Article Pathway analysis of genome-wide data improves warfarin dose prediction.
Academic Article Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
Academic Article Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells.
Academic Article Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.
Academic Article DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway.
Academic Article Isolation and characterization of a novel human gene, VANGL1, as a therapeutic target for hepatocellular carcinoma.
Academic Article Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
Academic Article Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
Academic Article Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy.
Academic Article Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
Academic Article Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis.
Academic Article Non-transmissible Sendai virus encoding granulocyte macrophage colony-stimulating factor is a novel and potent vector system for producing autologous tumor vaccines.
Academic Article Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors.
Academic Article In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy.
Academic Article Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).
Academic Article Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.
Academic Article Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor.
Academic Article Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
Academic Article Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
Academic Article CLCA2 as a p53-inducible senescence mediator.
Academic Article Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
Academic Article Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.
Academic Article Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
Academic Article WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
Academic Article Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma.
Academic Article Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
Academic Article The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
Academic Article Tumor budding is a significant indicator of a poor prognosis in lung squamous cell carcinoma patients.
Academic Article Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas.
Academic Article A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells.
Academic Article A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Academic Article Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools.
Academic Article Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
Academic Article Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
Academic Article Recombination rates of genes expressed in human tissues.
Academic Article Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10.
Academic Article Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer.
Academic Article Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
Academic Article HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.
Academic Article The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort.
Academic Article Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus.
Academic Article Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
Academic Article Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
Academic Article Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
Academic Article Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors.
Academic Article A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
Academic Article A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
Academic Article Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray.
Academic Article A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
Academic Article Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
Academic Article Serial analysis of gene expression in progressing and regressing mouse tumors implicates the involvement of RANTES and TARC in antitumor immune responses.
Academic Article Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
Academic Article Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study.
Academic Article An algorithm for inferring complex haplotypes in a region of copy-number variation.
Academic Article Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
Academic Article New correction algorithms for multiple comparisons in case-control multilocus association studies based on haplotypes and diplotype configurations.
Academic Article SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
Academic Article FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.
Academic Article Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
Academic Article TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis.
Academic Article Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
Academic Article Oncogenic role of MPHOSPH1, a cancer-testis antigen specific to human bladder cancer.
Academic Article Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
Academic Article SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.
Academic Article T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
Academic Article Regulation of iron homeostasis by the p53-ISCU pathway.
Academic Article Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Academic Article HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.
Academic Article Identification of CDCA1-derived long peptides bearing both CD4+ and CD8+ T-cell epitopes: CDCA1-specific CD4+ T-cell immunity in cancer patients.
Academic Article Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
Academic Article Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on radiosensitivity.
Academic Article Herpes simplex virus-induced, death receptor-dependent apoptosis and regression of transplanted human cancers.
Academic Article Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
Academic Article Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
Academic Article Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
Academic Article Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.
Academic Article The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
Academic Article Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
Academic Article T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
Academic Article WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
Academic Article GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Academic Article Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project.
Academic Article Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project.
Academic Article The Transcriptional Landscape of p53 Signalling Pathway.
Academic Article Third-generation oncolytic herpes simplex virus inhibits the growth of liver tumors in mice.
Academic Article Fukutin is required for maintenance of muscle integrity, cortical histiogenesis and normal eye development.
Academic Article miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.
Academic Article Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX.
Academic Article Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.
Academic Article Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility.
Academic Article a-particle therapy for synovial sarcoma in the mouse using an astatine-211-labeled antibody against frizzled homolog 10.
Academic Article Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
Academic Article Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
Academic Article CMOS-based bio-image sensor spatially resolves neural activity-dependent proton dynamics in the living brain.
Academic Article Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens.
Academic Article Enhancement of Migration and Invasion of Gastric Cancer Cells by IQGAP3.
Academic Article Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma.
Academic Article Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer.
Academic Article FZD10-targeted a-radioimmunotherapy with 225 Ac-labeled OTSA101 achieves complete remission in a synovial sarcoma model.
Academic Article Head-to-head comparison of three chelates reveals DOTAGA promising for 225 Ac labeling of anti-FZD10 antibody OTSA101.
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  • Hematologic Malignancies